• JAGS Invite
    December 09 12:00am
    Swim meet more »
  • 2016 IUPUI Holiday Night for Young Alumni
    December 09 6:30pm
    IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
  • IUPUI Holiday Night
    December 09 6:30pm
    Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
  • CLOSED
    December 10 12:00am
    Facility closed more »
  • JAGS Invite
    December 10 12:00am
    Swim meet more »
Friday, December 9, 2016
    IU Calendar




    • JAGS Invite
      December 09 12:00am
      Swim meet more »
    • 2016 IUPUI Holiday Night for Young Alumni
      December 09 6:30pm
      IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
    • IUPUI Holiday Night
      December 09 6:30pm
      Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
    • CLOSED
      December 10 12:00am
      Facility closed more »
    • JAGS Invite
      December 10 12:00am
      Swim meet more »
    Friday, December 9, 2016
      IU Calendar




      • JAGS Invite
        December 09 12:00am
        Swim meet more »
      • 2016 IUPUI Holiday Night for Young Alumni
        December 09 6:30pm
        IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
      • IUPUI Holiday Night
        December 09 6:30pm
        Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
      • CLOSED
        December 10 12:00am
        Facility closed more »
      • JAGS Invite
        December 10 12:00am
        Swim meet more »
      Friday, December 9, 2016
        IU Calendar




        • JAGS Invite
          December 09 12:00am
          Swim meet more »
        • 2016 IUPUI Holiday Night for Young Alumni
          December 09 6:30pm
          IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
        • IUPUI Holiday Night
          December 09 6:30pm
          Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
        • CLOSED
          December 10 12:00am
          Facility closed more »
        • JAGS Invite
          December 10 12:00am
          Swim meet more »
        Friday, December 9, 2016

          About This Event

          Summary

          Generating Practice-based Evidence from Electronic Health Records

          Abstract: In the era of EHRs, it is possible to examine the outcomes of decisions made by doctors during clinical practice to identify patterns of care that are optimal—generating evidence based on the collective practice of experts. We will discuss informatics methods that transform unstructured patient notes into a de-identified, temporally ordered, patient-feature matrix.  With the resulting high-throughput data, it is possible to monitor for adverse drug events, profile specific drugs, identify off-label drug usage, uncover ‘natural experiments’ and generate practice-based evidence for difficult-to-test clinical hypotheses. We will review four use-cases to illustrate the usefulness of learning practice-based evidence from unstructured clinical notes. 

          By examining the frequency and co-frequency of drug and disease mentions, we can detect associations among drugs and their adverse events about 2 years before an alert is issued as well as learn the prevalence of known drug-drug interactions. Using the patient feature matrix as well as prior knowledge about drugs, diseases, and known usage, we identify novel off-label uses; ranked on the basis of drug safety and cost. We uncover a natural experiment—a subset of CHF patients who were prescribed Cilostazol despite its black box warning—and profile its safety in this high-risk group of patients. We will discuss a use case of testing a clinical hypothesis about a possible association between allergic conditions and the complication of chronic uveitis in juvenile idiopathic arthritis (JIA) patients.

          Bio: Dr. Nigam Shah is assistant professor of Medicine (Biomedical Informatics) at Stanford University, where he Assistant Director of the Center for Biomedical Informatics Research, a member of the Biomedical Informatics Graduate Program and a core member of the National Center for Biomedical Ontology. His group develops methods to annotate, index and analyze large unstructured datasets for enabling use cases of the learning health system. His research has demonstrated that by using unstructured clinical data it is possible to monitor for adverse drug events, learn drug-drug interactions, identify off-label drug usage, find practice-based evidence for difficult-to-test clinical hypotheses, and generate phenotypic fingerprints of diseases.

          Dr. Shah received the AMIA New Investigator Award for 2013. Dr. Shah integrates teaching into his advanced research work and was recognized with the Biosciences Faculty Teaching Award for outstanding teaching contributions in his graduate class on “Data driven medicine” (Biomedin 215). He holds an MBBS from Baroda Medical College, India, a PhD from Penn State University and completed postdoctoral training at Stanford University. More at: https://cap.stanford.edu/profiles/stanford/Nigam_Shah

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          Contact Information

          Elizabeth Bunge
          ebunge@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • JAGS Invite
            December 09 12:00am
            Swim meet more »
          • 2016 IUPUI Holiday Night for Young Alumni
            December 09 6:30pm
            IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
          • IUPUI Holiday Night
            December 09 6:30pm
            Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
          • CLOSED
            December 10 12:00am
            Facility closed more »
          • JAGS Invite
            December 10 12:00am
            Swim meet more »
          Friday, December 9, 2016