• Competition Pool
    March 27 11:30am
    lap swim more »
  • Competition Pool
    March 28 5:30am
    lap swim more »
  • Phyllis Bramson | Love and Affection in a Hostile World
    March 28 10:00am
    A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
  • English Week: Building Community Partnerships Through Writing in W231
    March 28 11:00am
    Mary Ann Cohen, Dustin Branum, Sarah Grace Fraser, Taylor Gibbs, and Garad Huckleberry W231 introduces students to expanded research and writing skills and emphasizes the role of professional writing. As their main project, W231 students collaborate and solve a problem faced by a local business or organization. The teams conduct research to id more »
  • English Week: Graduate Student Experiences in the Teaching English Practicum
    March 28 12:00pm
    Julie Belz with Samantha Melvin, Esen Gokpinar-Shelton, Kim Robertson, and Kim Waletich The English Department at IUPUI offers two graduate degrees in Teaching English to Speakers of Other Languages (TESOL): a graduate certificate (18 credits) and an MA TESOL (31 credits). Five former and current TESOL students will speak about their d more »
Monday, March 27, 2017
    IU Calendar




    • Competition Pool
      March 27 11:30am
      lap swim more »
    • Competition Pool
      March 28 5:30am
      lap swim more »
    • Phyllis Bramson | Love and Affection in a Hostile World
      March 28 10:00am
      A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
    • English Week: Building Community Partnerships Through Writing in W231
      March 28 11:00am
      Mary Ann Cohen, Dustin Branum, Sarah Grace Fraser, Taylor Gibbs, and Garad Huckleberry W231 introduces students to expanded research and writing skills and emphasizes the role of professional writing. As their main project, W231 students collaborate and solve a problem faced by a local business or organization. The teams conduct research to id more »
    • English Week: Graduate Student Experiences in the Teaching English Practicum
      March 28 12:00pm
      Julie Belz with Samantha Melvin, Esen Gokpinar-Shelton, Kim Robertson, and Kim Waletich The English Department at IUPUI offers two graduate degrees in Teaching English to Speakers of Other Languages (TESOL): a graduate certificate (18 credits) and an MA TESOL (31 credits). Five former and current TESOL students will speak about their d more »
    Monday, March 27, 2017
      IU Calendar




      • Competition Pool
        March 27 11:30am
        lap swim more »
      • Competition Pool
        March 28 5:30am
        lap swim more »
      • Phyllis Bramson | Love and Affection in a Hostile World
        March 28 10:00am
        A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
      • English Week: Building Community Partnerships Through Writing in W231
        March 28 11:00am
        Mary Ann Cohen, Dustin Branum, Sarah Grace Fraser, Taylor Gibbs, and Garad Huckleberry W231 introduces students to expanded research and writing skills and emphasizes the role of professional writing. As their main project, W231 students collaborate and solve a problem faced by a local business or organization. The teams conduct research to id more »
      • English Week: Graduate Student Experiences in the Teaching English Practicum
        March 28 12:00pm
        Julie Belz with Samantha Melvin, Esen Gokpinar-Shelton, Kim Robertson, and Kim Waletich The English Department at IUPUI offers two graduate degrees in Teaching English to Speakers of Other Languages (TESOL): a graduate certificate (18 credits) and an MA TESOL (31 credits). Five former and current TESOL students will speak about their d more »
      Monday, March 27, 2017
        IU Calendar




        • Competition Pool
          March 27 11:30am
          lap swim more »
        • Competition Pool
          March 28 5:30am
          lap swim more »
        • Phyllis Bramson | Love and Affection in a Hostile World
          March 28 10:00am
          A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
        • English Week: Building Community Partnerships Through Writing in W231
          March 28 11:00am
          Mary Ann Cohen, Dustin Branum, Sarah Grace Fraser, Taylor Gibbs, and Garad Huckleberry W231 introduces students to expanded research and writing skills and emphasizes the role of professional writing. As their main project, W231 students collaborate and solve a problem faced by a local business or organization. The teams conduct research to id more »
        • English Week: Graduate Student Experiences in the Teaching English Practicum
          March 28 12:00pm
          Julie Belz with Samantha Melvin, Esen Gokpinar-Shelton, Kim Robertson, and Kim Waletich The English Department at IUPUI offers two graduate degrees in Teaching English to Speakers of Other Languages (TESOL): a graduate certificate (18 credits) and an MA TESOL (31 credits). Five former and current TESOL students will speak about their d more »
        Monday, March 27, 2017

          About This Event

          Summary

          Generating Practice-based Evidence from Electronic Health Records

          Abstract: In the era of EHRs, it is possible to examine the outcomes of decisions made by doctors during clinical practice to identify patterns of care that are optimal—generating evidence based on the collective practice of experts. We will discuss informatics methods that transform unstructured patient notes into a de-identified, temporally ordered, patient-feature matrix.  With the resulting high-throughput data, it is possible to monitor for adverse drug events, profile specific drugs, identify off-label drug usage, uncover ‘natural experiments’ and generate practice-based evidence for difficult-to-test clinical hypotheses. We will review four use-cases to illustrate the usefulness of learning practice-based evidence from unstructured clinical notes. 

          By examining the frequency and co-frequency of drug and disease mentions, we can detect associations among drugs and their adverse events about 2 years before an alert is issued as well as learn the prevalence of known drug-drug interactions. Using the patient feature matrix as well as prior knowledge about drugs, diseases, and known usage, we identify novel off-label uses; ranked on the basis of drug safety and cost. We uncover a natural experiment—a subset of CHF patients who were prescribed Cilostazol despite its black box warning—and profile its safety in this high-risk group of patients. We will discuss a use case of testing a clinical hypothesis about a possible association between allergic conditions and the complication of chronic uveitis in juvenile idiopathic arthritis (JIA) patients.

          Bio: Dr. Nigam Shah is assistant professor of Medicine (Biomedical Informatics) at Stanford University, where he Assistant Director of the Center for Biomedical Informatics Research, a member of the Biomedical Informatics Graduate Program and a core member of the National Center for Biomedical Ontology. His group develops methods to annotate, index and analyze large unstructured datasets for enabling use cases of the learning health system. His research has demonstrated that by using unstructured clinical data it is possible to monitor for adverse drug events, learn drug-drug interactions, identify off-label drug usage, find practice-based evidence for difficult-to-test clinical hypotheses, and generate phenotypic fingerprints of diseases.

          Dr. Shah received the AMIA New Investigator Award for 2013. Dr. Shah integrates teaching into his advanced research work and was recognized with the Biosciences Faculty Teaching Award for outstanding teaching contributions in his graduate class on “Data driven medicine” (Biomedin 215). He holds an MBBS from Baroda Medical College, India, a PhD from Penn State University and completed postdoctoral training at Stanford University. More at: https://cap.stanford.edu/profiles/stanford/Nigam_Shah

          Bookmark and Share
          Contact Information

          Elizabeth Bunge
          ebunge@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • Competition Pool
            March 27 11:30am
            lap swim more »
          • Competition Pool
            March 28 5:30am
            lap swim more »
          • Phyllis Bramson | Love and Affection in a Hostile World
            March 28 10:00am
            A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
          • English Week: Building Community Partnerships Through Writing in W231
            March 28 11:00am
            Mary Ann Cohen, Dustin Branum, Sarah Grace Fraser, Taylor Gibbs, and Garad Huckleberry W231 introduces students to expanded research and writing skills and emphasizes the role of professional writing. As their main project, W231 students collaborate and solve a problem faced by a local business or organization. The teams conduct research to id more »
          • English Week: Graduate Student Experiences in the Teaching English Practicum
            March 28 12:00pm
            Julie Belz with Samantha Melvin, Esen Gokpinar-Shelton, Kim Robertson, and Kim Waletich The English Department at IUPUI offers two graduate degrees in Teaching English to Speakers of Other Languages (TESOL): a graduate certificate (18 credits) and an MA TESOL (31 credits). Five former and current TESOL students will speak about their d more »
          Monday, March 27, 2017