• Competition Pool
    February 22 5:30am
    lap swim more »
  • STI/HIV Testing
    February 22 10:00am
    Stop by the LGBTQ+ Center for free STI/HIV testing. Testing is free, safe and confidential. Tests include HIV, Syphilis, Chlamydia, and Gonorrhea. Testing is conducted by the Bellflower Clinic of the Marion County Health Department. No appointment necessary.  more »
  • Hans Op de Beeck | Staging Silence (2)
    February 22 10:00am
    In Belgian artist Hans Op de Beeck's film, the real and the imaginary fuse as anonymous hands assemble miniature dioramas of timeless, dreamlike settings. more »
  • IUPUI's 13th Annual International Festival
    February 22 10:30am
    IUPUI’s 13th Annual International Festival! You are invited to eat, explore, and engage in IUPUI’s global community at the International Festival: - Eat FREE FOOD from around the world - Explore international opportunities on campus and in the community - Engage with international student groups, community organizations and globa more »
  • Teaching @IUPUI: Motivating Students to Prepare for Class
    February 22 11:30am
    Getting students to come to class prepared can be a challenge but is essential to making in-class time productive. In this session, participants will learn strategies to guide students’ pre-class learning, to make explicit the relevance of pre-class work, and to assess students’ preparation. more »
Wednesday, February 22, 2017
    IU Calendar




    • Competition Pool
      February 22 5:30am
      lap swim more »
    • STI/HIV Testing
      February 22 10:00am
      Stop by the LGBTQ+ Center for free STI/HIV testing. Testing is free, safe and confidential. Tests include HIV, Syphilis, Chlamydia, and Gonorrhea. Testing is conducted by the Bellflower Clinic of the Marion County Health Department. No appointment necessary.  more »
    • Hans Op de Beeck | Staging Silence (2)
      February 22 10:00am
      In Belgian artist Hans Op de Beeck's film, the real and the imaginary fuse as anonymous hands assemble miniature dioramas of timeless, dreamlike settings. more »
    • IUPUI's 13th Annual International Festival
      February 22 10:30am
      IUPUI’s 13th Annual International Festival! You are invited to eat, explore, and engage in IUPUI’s global community at the International Festival: - Eat FREE FOOD from around the world - Explore international opportunities on campus and in the community - Engage with international student groups, community organizations and globa more »
    • Teaching @IUPUI: Motivating Students to Prepare for Class
      February 22 11:30am
      Getting students to come to class prepared can be a challenge but is essential to making in-class time productive. In this session, participants will learn strategies to guide students’ pre-class learning, to make explicit the relevance of pre-class work, and to assess students’ preparation. more »
    Wednesday, February 22, 2017
      IU Calendar




      • Competition Pool
        February 22 5:30am
        lap swim more »
      • STI/HIV Testing
        February 22 10:00am
        Stop by the LGBTQ+ Center for free STI/HIV testing. Testing is free, safe and confidential. Tests include HIV, Syphilis, Chlamydia, and Gonorrhea. Testing is conducted by the Bellflower Clinic of the Marion County Health Department. No appointment necessary.  more »
      • Hans Op de Beeck | Staging Silence (2)
        February 22 10:00am
        In Belgian artist Hans Op de Beeck's film, the real and the imaginary fuse as anonymous hands assemble miniature dioramas of timeless, dreamlike settings. more »
      • IUPUI's 13th Annual International Festival
        February 22 10:30am
        IUPUI’s 13th Annual International Festival! You are invited to eat, explore, and engage in IUPUI’s global community at the International Festival: - Eat FREE FOOD from around the world - Explore international opportunities on campus and in the community - Engage with international student groups, community organizations and globa more »
      • Teaching @IUPUI: Motivating Students to Prepare for Class
        February 22 11:30am
        Getting students to come to class prepared can be a challenge but is essential to making in-class time productive. In this session, participants will learn strategies to guide students’ pre-class learning, to make explicit the relevance of pre-class work, and to assess students’ preparation. more »
      Wednesday, February 22, 2017
        IU Calendar




        • Competition Pool
          February 22 5:30am
          lap swim more »
        • STI/HIV Testing
          February 22 10:00am
          Stop by the LGBTQ+ Center for free STI/HIV testing. Testing is free, safe and confidential. Tests include HIV, Syphilis, Chlamydia, and Gonorrhea. Testing is conducted by the Bellflower Clinic of the Marion County Health Department. No appointment necessary.  more »
        • Hans Op de Beeck | Staging Silence (2)
          February 22 10:00am
          In Belgian artist Hans Op de Beeck's film, the real and the imaginary fuse as anonymous hands assemble miniature dioramas of timeless, dreamlike settings. more »
        • IUPUI's 13th Annual International Festival
          February 22 10:30am
          IUPUI’s 13th Annual International Festival! You are invited to eat, explore, and engage in IUPUI’s global community at the International Festival: - Eat FREE FOOD from around the world - Explore international opportunities on campus and in the community - Engage with international student groups, community organizations and globa more »
        • Teaching @IUPUI: Motivating Students to Prepare for Class
          February 22 11:30am
          Getting students to come to class prepared can be a challenge but is essential to making in-class time productive. In this session, participants will learn strategies to guide students’ pre-class learning, to make explicit the relevance of pre-class work, and to assess students’ preparation. more »
        Wednesday, February 22, 2017

          About This Event

          Summary

          Generating Practice-based Evidence from Electronic Health Records

          Abstract: In the era of EHRs, it is possible to examine the outcomes of decisions made by doctors during clinical practice to identify patterns of care that are optimal—generating evidence based on the collective practice of experts. We will discuss informatics methods that transform unstructured patient notes into a de-identified, temporally ordered, patient-feature matrix.  With the resulting high-throughput data, it is possible to monitor for adverse drug events, profile specific drugs, identify off-label drug usage, uncover ‘natural experiments’ and generate practice-based evidence for difficult-to-test clinical hypotheses. We will review four use-cases to illustrate the usefulness of learning practice-based evidence from unstructured clinical notes. 

          By examining the frequency and co-frequency of drug and disease mentions, we can detect associations among drugs and their adverse events about 2 years before an alert is issued as well as learn the prevalence of known drug-drug interactions. Using the patient feature matrix as well as prior knowledge about drugs, diseases, and known usage, we identify novel off-label uses; ranked on the basis of drug safety and cost. We uncover a natural experiment—a subset of CHF patients who were prescribed Cilostazol despite its black box warning—and profile its safety in this high-risk group of patients. We will discuss a use case of testing a clinical hypothesis about a possible association between allergic conditions and the complication of chronic uveitis in juvenile idiopathic arthritis (JIA) patients.

          Bio: Dr. Nigam Shah is assistant professor of Medicine (Biomedical Informatics) at Stanford University, where he Assistant Director of the Center for Biomedical Informatics Research, a member of the Biomedical Informatics Graduate Program and a core member of the National Center for Biomedical Ontology. His group develops methods to annotate, index and analyze large unstructured datasets for enabling use cases of the learning health system. His research has demonstrated that by using unstructured clinical data it is possible to monitor for adverse drug events, learn drug-drug interactions, identify off-label drug usage, find practice-based evidence for difficult-to-test clinical hypotheses, and generate phenotypic fingerprints of diseases.

          Dr. Shah received the AMIA New Investigator Award for 2013. Dr. Shah integrates teaching into his advanced research work and was recognized with the Biosciences Faculty Teaching Award for outstanding teaching contributions in his graduate class on “Data driven medicine” (Biomedin 215). He holds an MBBS from Baroda Medical College, India, a PhD from Penn State University and completed postdoctoral training at Stanford University. More at: https://cap.stanford.edu/profiles/stanford/Nigam_Shah

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          Contact Information

          Elizabeth Bunge
          ebunge@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • Competition Pool
            February 22 5:30am
            lap swim more »
          • STI/HIV Testing
            February 22 10:00am
            Stop by the LGBTQ+ Center for free STI/HIV testing. Testing is free, safe and confidential. Tests include HIV, Syphilis, Chlamydia, and Gonorrhea. Testing is conducted by the Bellflower Clinic of the Marion County Health Department. No appointment necessary.  more »
          • Hans Op de Beeck | Staging Silence (2)
            February 22 10:00am
            In Belgian artist Hans Op de Beeck's film, the real and the imaginary fuse as anonymous hands assemble miniature dioramas of timeless, dreamlike settings. more »
          • IUPUI's 13th Annual International Festival
            February 22 10:30am
            IUPUI’s 13th Annual International Festival! You are invited to eat, explore, and engage in IUPUI’s global community at the International Festival: - Eat FREE FOOD from around the world - Explore international opportunities on campus and in the community - Engage with international student groups, community organizations and globa more »
          • Teaching @IUPUI: Motivating Students to Prepare for Class
            February 22 11:30am
            Getting students to come to class prepared can be a challenge but is essential to making in-class time productive. In this session, participants will learn strategies to guide students’ pre-class learning, to make explicit the relevance of pre-class work, and to assess students’ preparation. more »
          Wednesday, February 22, 2017