• CLD Success Prep
    October 21 8:00am
    Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
  • Homecoming: Day of Caring
    October 21 8:00am
    Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
  • IUPUI United Way Day of Caring
    October 21 9:00am
    Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
  • Homecoming: NPHC Step Show
    October 21 6:30pm
    As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
  • CLOSED
    October 22 12:00am
    The competition lap pool for lap swim is closed. more »
Saturday, October 21, 2017
    IU Calendar




    • CLD Success Prep
      October 21 8:00am
      Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
    • Homecoming: Day of Caring
      October 21 8:00am
      Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
    • IUPUI United Way Day of Caring
      October 21 9:00am
      Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
    • Homecoming: NPHC Step Show
      October 21 6:30pm
      As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
    • CLOSED
      October 22 12:00am
      The competition lap pool for lap swim is closed. more »
    Saturday, October 21, 2017
      IU Calendar




      • CLD Success Prep
        October 21 8:00am
        Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
      • Homecoming: Day of Caring
        October 21 8:00am
        Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
      • IUPUI United Way Day of Caring
        October 21 9:00am
        Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
      • Homecoming: NPHC Step Show
        October 21 6:30pm
        As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
      • CLOSED
        October 22 12:00am
        The competition lap pool for lap swim is closed. more »
      Saturday, October 21, 2017
        IU Calendar




        • CLD Success Prep
          October 21 8:00am
          Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
        • Homecoming: Day of Caring
          October 21 8:00am
          Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
        • IUPUI United Way Day of Caring
          October 21 9:00am
          Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
        • Homecoming: NPHC Step Show
          October 21 6:30pm
          As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
        • CLOSED
          October 22 12:00am
          The competition lap pool for lap swim is closed. more »
        Saturday, October 21, 2017

          About This Event

          Summary

          Generating Practice-based Evidence from Electronic Health Records

          Abstract: In the era of EHRs, it is possible to examine the outcomes of decisions made by doctors during clinical practice to identify patterns of care that are optimal—generating evidence based on the collective practice of experts. We will discuss informatics methods that transform unstructured patient notes into a de-identified, temporally ordered, patient-feature matrix.  With the resulting high-throughput data, it is possible to monitor for adverse drug events, profile specific drugs, identify off-label drug usage, uncover ‘natural experiments’ and generate practice-based evidence for difficult-to-test clinical hypotheses. We will review four use-cases to illustrate the usefulness of learning practice-based evidence from unstructured clinical notes. 

          By examining the frequency and co-frequency of drug and disease mentions, we can detect associations among drugs and their adverse events about 2 years before an alert is issued as well as learn the prevalence of known drug-drug interactions. Using the patient feature matrix as well as prior knowledge about drugs, diseases, and known usage, we identify novel off-label uses; ranked on the basis of drug safety and cost. We uncover a natural experiment—a subset of CHF patients who were prescribed Cilostazol despite its black box warning—and profile its safety in this high-risk group of patients. We will discuss a use case of testing a clinical hypothesis about a possible association between allergic conditions and the complication of chronic uveitis in juvenile idiopathic arthritis (JIA) patients.

          Bio: Dr. Nigam Shah is assistant professor of Medicine (Biomedical Informatics) at Stanford University, where he Assistant Director of the Center for Biomedical Informatics Research, a member of the Biomedical Informatics Graduate Program and a core member of the National Center for Biomedical Ontology. His group develops methods to annotate, index and analyze large unstructured datasets for enabling use cases of the learning health system. His research has demonstrated that by using unstructured clinical data it is possible to monitor for adverse drug events, learn drug-drug interactions, identify off-label drug usage, find practice-based evidence for difficult-to-test clinical hypotheses, and generate phenotypic fingerprints of diseases.

          Dr. Shah received the AMIA New Investigator Award for 2013. Dr. Shah integrates teaching into his advanced research work and was recognized with the Biosciences Faculty Teaching Award for outstanding teaching contributions in his graduate class on “Data driven medicine” (Biomedin 215). He holds an MBBS from Baroda Medical College, India, a PhD from Penn State University and completed postdoctoral training at Stanford University. More at: https://cap.stanford.edu/profiles/stanford/Nigam_Shah

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          Contact Information

          Elizabeth Bunge
          ebunge@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • CLD Success Prep
            October 21 8:00am
            Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
          • Homecoming: Day of Caring
            October 21 8:00am
            Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
          • IUPUI United Way Day of Caring
            October 21 9:00am
            Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
          • Homecoming: NPHC Step Show
            October 21 6:30pm
            As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
          • CLOSED
            October 22 12:00am
            The competition lap pool for lap swim is closed. more »
          Saturday, October 21, 2017