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    May 30 9:00am
    This workshop lasts 3 hours, and is part of the certificate series Access 2016 End-User Relationships are the fundamental building blocks of complex databases and are critical to designing and working with sophisticated databases. This workshop is intended for participants who are familiar with the ba more »
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    May 30 9:00am
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Monday, May 29, 2017
    IU Calendar




    • CLOSED - Memorial Day
      May 29 12:00am
      Closed more »
    • Competition Pool
      May 30 5:30am
      Lap Swim more »
    • Instructional Pool
      May 30 7:00am
      Lap Swim  more »
    • Access 2016: Structuring & Relating Data
      May 30 9:00am
      This workshop lasts 3 hours, and is part of the certificate series Access 2016 End-User Relationships are the fundamental building blocks of complex databases and are critical to designing and working with sophisticated databases. This workshop is intended for participants who are familiar with the ba more »
    • Competition Pool
      May 30 9:00am
      Lap Swim more »
    Monday, May 29, 2017
      IU Calendar




      • CLOSED - Memorial Day
        May 29 12:00am
        Closed more »
      • Competition Pool
        May 30 5:30am
        Lap Swim more »
      • Instructional Pool
        May 30 7:00am
        Lap Swim  more »
      • Access 2016: Structuring & Relating Data
        May 30 9:00am
        This workshop lasts 3 hours, and is part of the certificate series Access 2016 End-User Relationships are the fundamental building blocks of complex databases and are critical to designing and working with sophisticated databases. This workshop is intended for participants who are familiar with the ba more »
      • Competition Pool
        May 30 9:00am
        Lap Swim more »
      Monday, May 29, 2017
        IU Calendar




        • CLOSED - Memorial Day
          May 29 12:00am
          Closed more »
        • Competition Pool
          May 30 5:30am
          Lap Swim more »
        • Instructional Pool
          May 30 7:00am
          Lap Swim  more »
        • Access 2016: Structuring & Relating Data
          May 30 9:00am
          This workshop lasts 3 hours, and is part of the certificate series Access 2016 End-User Relationships are the fundamental building blocks of complex databases and are critical to designing and working with sophisticated databases. This workshop is intended for participants who are familiar with the ba more »
        • Competition Pool
          May 30 9:00am
          Lap Swim more »
        Monday, May 29, 2017

          About This Event

          Summary

           

          Abstract: Proving that a drug that has seen human patients also works in another indication adds clear value for patients. The question for informatics is can these predictions be made systematically with precision. We will discuss two recent methods that add to this debate. The first one uses genetics associations (from Genome Wide Association Studies – GWAS) to find new indications for drugs some of which are being validated experimentally. The second one frames the side effects of drugs as pharmacological effects, relies on the observation that many drugs that treat a disease have similar side effects, and then predicts other drugs with similar side effects as potential treatments for the disease. In addition, we will discuss other techniques that use text mining, compound-based methods such as connectivity map, electronic health records, and other public data. We hope that the field of drug repositioning will continue to be a showcase for informatics techniques in medicine.

           

          Bio: Pankaj Agarwal obtained a B. Tech. in Computer Science & Engineering from IIT, Delhi. His Ph.D. is in Computer Science from the Courant Institute, New York University. His thesis was on “Cell-based Computer Models in Developmental Biology”. Pankaj did a postdoc in Bioinformatics at the Washington University, St. Louis, MO. He was one of the founding members and directors of the International Society for Computational Biology (ISCB). Since 1996, he has been at GlaxoSmithKline, and has led on a number of projects to mine biological data in to demonstrate informatics value for the pharmaceutical industry. He leads the Systematic Drug Repositioning group at GSK and his research is focused on computational methods for discovering the right disease indication for drugs.

           

           

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          IU Calendar




          • CLOSED - Memorial Day
            May 29 12:00am
            Closed more »
          • Competition Pool
            May 30 5:30am
            Lap Swim more »
          • Instructional Pool
            May 30 7:00am
            Lap Swim  more »
          • Access 2016: Structuring & Relating Data
            May 30 9:00am
            This workshop lasts 3 hours, and is part of the certificate series Access 2016 End-User Relationships are the fundamental building blocks of complex databases and are critical to designing and working with sophisticated databases. This workshop is intended for participants who are familiar with the ba more »
          • Competition Pool
            May 30 9:00am
            Lap Swim more »
          Monday, May 29, 2017