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    January 22 11:30am
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    January 22 1:30pm
    Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
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    January 22 3:45pm
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    January 22 4:30pm
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    January 23 12:00am
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Monday, January 22, 2018
    IU Calendar




    • Competition Pool
      January 22 11:30am
      Lap Swim more »
    • Substance Abuse Recovery Support Meeting
      January 22 1:30pm
      Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
    • Instructional Pool
      January 22 3:45pm
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    • Competition Pool
      January 22 4:30pm
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    • Brebeuf Invite
      January 23 12:00am
      Swim Meet more »
    Monday, January 22, 2018
      IU Calendar




      • Competition Pool
        January 22 11:30am
        Lap Swim more »
      • Substance Abuse Recovery Support Meeting
        January 22 1:30pm
        Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
      • Instructional Pool
        January 22 3:45pm
        Lap Swim more »
      • Competition Pool
        January 22 4:30pm
        Lap Swim more »
      • Brebeuf Invite
        January 23 12:00am
        Swim Meet more »
      Monday, January 22, 2018
        IU Calendar




        • Competition Pool
          January 22 11:30am
          Lap Swim more »
        • Substance Abuse Recovery Support Meeting
          January 22 1:30pm
          Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
        • Instructional Pool
          January 22 3:45pm
          Lap Swim more »
        • Competition Pool
          January 22 4:30pm
          Lap Swim more »
        • Brebeuf Invite
          January 23 12:00am
          Swim Meet more »
        Monday, January 22, 2018

          About This Event

          Summary

           

          Abstract: Proving that a drug that has seen human patients also works in another indication adds clear value for patients. The question for informatics is can these predictions be made systematically with precision. We will discuss two recent methods that add to this debate. The first one uses genetics associations (from Genome Wide Association Studies – GWAS) to find new indications for drugs some of which are being validated experimentally. The second one frames the side effects of drugs as pharmacological effects, relies on the observation that many drugs that treat a disease have similar side effects, and then predicts other drugs with similar side effects as potential treatments for the disease. In addition, we will discuss other techniques that use text mining, compound-based methods such as connectivity map, electronic health records, and other public data. We hope that the field of drug repositioning will continue to be a showcase for informatics techniques in medicine.

           

          Bio: Pankaj Agarwal obtained a B. Tech. in Computer Science & Engineering from IIT, Delhi. His Ph.D. is in Computer Science from the Courant Institute, New York University. His thesis was on “Cell-based Computer Models in Developmental Biology”. Pankaj did a postdoc in Bioinformatics at the Washington University, St. Louis, MO. He was one of the founding members and directors of the International Society for Computational Biology (ISCB). Since 1996, he has been at GlaxoSmithKline, and has led on a number of projects to mine biological data in to demonstrate informatics value for the pharmaceutical industry. He leads the Systematic Drug Repositioning group at GSK and his research is focused on computational methods for discovering the right disease indication for drugs.

           

           

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          IU Calendar




          • Competition Pool
            January 22 11:30am
            Lap Swim more »
          • Substance Abuse Recovery Support Meeting
            January 22 1:30pm
            Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
          • Instructional Pool
            January 22 3:45pm
            Lap Swim more »
          • Competition Pool
            January 22 4:30pm
            Lap Swim more »
          • Brebeuf Invite
            January 23 12:00am
            Swim Meet more »
          Monday, January 22, 2018