• CLOSED
    February 26 12:00am
    The competition lap pool for lap swim is closed. more »
  • Limited 50m lanes available
    February 27 12:00am
    lap swim more »
  • American English for International Professionals - Deadline May 31st!
    February 27 12:00am
    ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
  • Competition Pool
    February 27 5:30am
    lap swim more »
  • Freya Powell | Omniscience and Oblivion
    February 27 10:00am
    For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
Sunday, February 26, 2017
    IU Calendar




    • CLOSED
      February 26 12:00am
      The competition lap pool for lap swim is closed. more »
    • Limited 50m lanes available
      February 27 12:00am
      lap swim more »
    • American English for International Professionals - Deadline May 31st!
      February 27 12:00am
      ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
    • Competition Pool
      February 27 5:30am
      lap swim more »
    • Freya Powell | Omniscience and Oblivion
      February 27 10:00am
      For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
    Sunday, February 26, 2017
      IU Calendar




      • CLOSED
        February 26 12:00am
        The competition lap pool for lap swim is closed. more »
      • Limited 50m lanes available
        February 27 12:00am
        lap swim more »
      • American English for International Professionals - Deadline May 31st!
        February 27 12:00am
        ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
      • Competition Pool
        February 27 5:30am
        lap swim more »
      • Freya Powell | Omniscience and Oblivion
        February 27 10:00am
        For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
      Sunday, February 26, 2017
        IU Calendar




        • CLOSED
          February 26 12:00am
          The competition lap pool for lap swim is closed. more »
        • Limited 50m lanes available
          February 27 12:00am
          lap swim more »
        • American English for International Professionals - Deadline May 31st!
          February 27 12:00am
          ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
        • Competition Pool
          February 27 5:30am
          lap swim more »
        • Freya Powell | Omniscience and Oblivion
          February 27 10:00am
          For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
        Sunday, February 26, 2017

          About This Event

          Summary

          Abstract: In this talk, I will introduce two new computational problems stemming from the analysis of next-generation sequencing data. In the first, I will describe the problem of determining the position of nucleosomes in a genome (nucleosomes are the basic elements of DNA chromatin structure). We solved this problem using a method based on a modified Gaussian mixture model. An expectation maximization (EM) algorithm is used to infer the parameters of the mixture of distributions.

          In the second, I will briefly address the problem of obtaining the primary sequence for large, complex genomes. We propose a BAC-by-BAC sequencing protocol that leverages recent advances in combinatorial pooling design (group testing). I will show that combinatorial pooling is a cost-effective and practical alternative to exhaustive DNA barcoding when preparing sequencing libraries for hundreds or thousands of DNA samples, such as in this case case gene-bearing BAC clones.

           

          Bio: Stefano Lonardi is Professor and Vice Chair of the Department of Computer Science and Engineering at University of California, Riverside, CA. He is also a faculty member of the Graduate Program in Genetics, Genomics and Bioinformatics, the Center for Plant Cell Biology, the Institute for Integrative Genome Biology, and the Graduate Program in Cell, Molecular and Developmental Biology.

          Stefano received his Laurea cum laude from University of Pisa in 1994 and his Ph.D. in the summer of 2001 from the Department of Computer Sciences, Purdue University, West Lafayette, IN.  He also holds a doctorate degree in Electrical and Information Engineering from University of Padua (1999). During the summer of 1999, he was intern at Celera Genomics, Department of Informatics Research, Rockville, MD.

          Stefano's recent research interest includes design of algorithms, computational molecular biology, data compression and data mining. He has published over 40 papers in major theoretical computer science and computational biology journals and over 50 publications in refereed international conferences. In the year 2005, he received the CAREER award from National Science Foundation. He has received funding from NSF, NIH, DARPA, and USDA.

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          IU Calendar




          • CLOSED
            February 26 12:00am
            The competition lap pool for lap swim is closed. more »
          • Limited 50m lanes available
            February 27 12:00am
            lap swim more »
          • American English for International Professionals - Deadline May 31st!
            February 27 12:00am
            ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
          • Competition Pool
            February 27 5:30am
            lap swim more »
          • Freya Powell | Omniscience and Oblivion
            February 27 10:00am
            For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
          Sunday, February 26, 2017