• Competition Pool
    February 19 11:30am
    Lap Swim more »
  • Substance Abuse Recovery Support Meeting
    February 19 1:30pm
    Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
  • 2018 WOW Student Steering Committee Callout
    February 19 3:00pm
    Looking for opportunities to get involved on campus? Like working in a group? Have an extra 2 - 5 hours a week? If so, attend our upcoming Information Session about the 2018 Weeks of Welcome Student Steering Committee. Mandy Porter, Coordinator for Student Success and Outreach, will be presenting on the different roles you can get involved more »
  • Competition Pool
    February 19 4:30pm
    Lap Swim more »
  • Economic Justice and Doing Business with the Poor: The Cummins Experience
    February 19 7:00pm
    You are invited to hear Mark Sifferlen, Cummins' Vice President of Ethics and Compliance talk about his experiences.  Open to the public, food will be provided. more »
Monday, February 19, 2018
    IU Calendar




    • Competition Pool
      February 19 11:30am
      Lap Swim more »
    • Substance Abuse Recovery Support Meeting
      February 19 1:30pm
      Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
    • 2018 WOW Student Steering Committee Callout
      February 19 3:00pm
      Looking for opportunities to get involved on campus? Like working in a group? Have an extra 2 - 5 hours a week? If so, attend our upcoming Information Session about the 2018 Weeks of Welcome Student Steering Committee. Mandy Porter, Coordinator for Student Success and Outreach, will be presenting on the different roles you can get involved more »
    • Competition Pool
      February 19 4:30pm
      Lap Swim more »
    • Economic Justice and Doing Business with the Poor: The Cummins Experience
      February 19 7:00pm
      You are invited to hear Mark Sifferlen, Cummins' Vice President of Ethics and Compliance talk about his experiences.  Open to the public, food will be provided. more »
    Monday, February 19, 2018
      IU Calendar




      • Competition Pool
        February 19 11:30am
        Lap Swim more »
      • Substance Abuse Recovery Support Meeting
        February 19 1:30pm
        Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
      • 2018 WOW Student Steering Committee Callout
        February 19 3:00pm
        Looking for opportunities to get involved on campus? Like working in a group? Have an extra 2 - 5 hours a week? If so, attend our upcoming Information Session about the 2018 Weeks of Welcome Student Steering Committee. Mandy Porter, Coordinator for Student Success and Outreach, will be presenting on the different roles you can get involved more »
      • Competition Pool
        February 19 4:30pm
        Lap Swim more »
      • Economic Justice and Doing Business with the Poor: The Cummins Experience
        February 19 7:00pm
        You are invited to hear Mark Sifferlen, Cummins' Vice President of Ethics and Compliance talk about his experiences.  Open to the public, food will be provided. more »
      Monday, February 19, 2018
        IU Calendar




        • Competition Pool
          February 19 11:30am
          Lap Swim more »
        • Substance Abuse Recovery Support Meeting
          February 19 1:30pm
          Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
        • 2018 WOW Student Steering Committee Callout
          February 19 3:00pm
          Looking for opportunities to get involved on campus? Like working in a group? Have an extra 2 - 5 hours a week? If so, attend our upcoming Information Session about the 2018 Weeks of Welcome Student Steering Committee. Mandy Porter, Coordinator for Student Success and Outreach, will be presenting on the different roles you can get involved more »
        • Competition Pool
          February 19 4:30pm
          Lap Swim more »
        • Economic Justice and Doing Business with the Poor: The Cummins Experience
          February 19 7:00pm
          You are invited to hear Mark Sifferlen, Cummins' Vice President of Ethics and Compliance talk about his experiences.  Open to the public, food will be provided. more »
        Monday, February 19, 2018

          About This Event

          Summary

          Abstract: In this talk, I will introduce two new computational problems stemming from the analysis of next-generation sequencing data. In the first, I will describe the problem of determining the position of nucleosomes in a genome (nucleosomes are the basic elements of DNA chromatin structure). We solved this problem using a method based on a modified Gaussian mixture model. An expectation maximization (EM) algorithm is used to infer the parameters of the mixture of distributions.

          In the second, I will briefly address the problem of obtaining the primary sequence for large, complex genomes. We propose a BAC-by-BAC sequencing protocol that leverages recent advances in combinatorial pooling design (group testing). I will show that combinatorial pooling is a cost-effective and practical alternative to exhaustive DNA barcoding when preparing sequencing libraries for hundreds or thousands of DNA samples, such as in this case case gene-bearing BAC clones.

           

          Bio: Stefano Lonardi is Professor and Vice Chair of the Department of Computer Science and Engineering at University of California, Riverside, CA. He is also a faculty member of the Graduate Program in Genetics, Genomics and Bioinformatics, the Center for Plant Cell Biology, the Institute for Integrative Genome Biology, and the Graduate Program in Cell, Molecular and Developmental Biology.

          Stefano received his Laurea cum laude from University of Pisa in 1994 and his Ph.D. in the summer of 2001 from the Department of Computer Sciences, Purdue University, West Lafayette, IN.  He also holds a doctorate degree in Electrical and Information Engineering from University of Padua (1999). During the summer of 1999, he was intern at Celera Genomics, Department of Informatics Research, Rockville, MD.

          Stefano's recent research interest includes design of algorithms, computational molecular biology, data compression and data mining. He has published over 40 papers in major theoretical computer science and computational biology journals and over 50 publications in refereed international conferences. In the year 2005, he received the CAREER award from National Science Foundation. He has received funding from NSF, NIH, DARPA, and USDA.

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          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • Competition Pool
            February 19 11:30am
            Lap Swim more »
          • Substance Abuse Recovery Support Meeting
            February 19 1:30pm
            Weekly peer support and discussion-based meetings for students in recovery from alcohol or drug abuse/addiction. We respect anonymity. Join us for these non-clinical student-led meetings to continue your path to recovery. more »
          • 2018 WOW Student Steering Committee Callout
            February 19 3:00pm
            Looking for opportunities to get involved on campus? Like working in a group? Have an extra 2 - 5 hours a week? If so, attend our upcoming Information Session about the 2018 Weeks of Welcome Student Steering Committee. Mandy Porter, Coordinator for Student Success and Outreach, will be presenting on the different roles you can get involved more »
          • Competition Pool
            February 19 4:30pm
            Lap Swim more »
          • Economic Justice and Doing Business with the Poor: The Cummins Experience
            February 19 7:00pm
            You are invited to hear Mark Sifferlen, Cummins' Vice President of Ethics and Compliance talk about his experiences.  Open to the public, food will be provided. more »
          Monday, February 19, 2018