• Speedo Champions Series
    March 29 12:00am
    Swim Meet more »
  • Phyllis Bramson | Love and Affection in a Hostile World
    March 29 10:00am
    A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
  • Philip Powell presents Business and the Poor:The Ethics and the Economics
    March 29 7:00pm
    The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
  • Philip Powell presents Business and the Poor:The Ethics and the Economics
    March 29 7:00pm
    The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
  • The Rufus and Louise Reiberg Reading Series presents Angela Palm
    March 29 7:30pm
    A native of Indiana, Angela Palm is the author of Riverine: A Memoir from Anywhere but Here, published by Graywolf Press in 2016. She owns Ink + Lead Literary Services and is the editor of an anthology of Vermont writers, Please Do Not Remove. Her work has appeared in Paper Darts, Midwestern Gothic, Tampa Review, and elsewhere. She lives in Burl more »
Wednesday, March 29, 2017
    IU Calendar




    • Speedo Champions Series
      March 29 12:00am
      Swim Meet more »
    • Phyllis Bramson | Love and Affection in a Hostile World
      March 29 10:00am
      A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
    • Philip Powell presents Business and the Poor:The Ethics and the Economics
      March 29 7:00pm
      The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
    • Philip Powell presents Business and the Poor:The Ethics and the Economics
      March 29 7:00pm
      The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
    • The Rufus and Louise Reiberg Reading Series presents Angela Palm
      March 29 7:30pm
      A native of Indiana, Angela Palm is the author of Riverine: A Memoir from Anywhere but Here, published by Graywolf Press in 2016. She owns Ink + Lead Literary Services and is the editor of an anthology of Vermont writers, Please Do Not Remove. Her work has appeared in Paper Darts, Midwestern Gothic, Tampa Review, and elsewhere. She lives in Burl more »
    Wednesday, March 29, 2017
      IU Calendar




      • Speedo Champions Series
        March 29 12:00am
        Swim Meet more »
      • Phyllis Bramson | Love and Affection in a Hostile World
        March 29 10:00am
        A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
      • Philip Powell presents Business and the Poor:The Ethics and the Economics
        March 29 7:00pm
        The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
      • Philip Powell presents Business and the Poor:The Ethics and the Economics
        March 29 7:00pm
        The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
      • The Rufus and Louise Reiberg Reading Series presents Angela Palm
        March 29 7:30pm
        A native of Indiana, Angela Palm is the author of Riverine: A Memoir from Anywhere but Here, published by Graywolf Press in 2016. She owns Ink + Lead Literary Services and is the editor of an anthology of Vermont writers, Please Do Not Remove. Her work has appeared in Paper Darts, Midwestern Gothic, Tampa Review, and elsewhere. She lives in Burl more »
      Wednesday, March 29, 2017
        IU Calendar




        • Speedo Champions Series
          March 29 12:00am
          Swim Meet more »
        • Phyllis Bramson | Love and Affection in a Hostile World
          March 29 10:00am
          A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
        • Philip Powell presents Business and the Poor:The Ethics and the Economics
          March 29 7:00pm
          The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
        • Philip Powell presents Business and the Poor:The Ethics and the Economics
          March 29 7:00pm
          The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
        • The Rufus and Louise Reiberg Reading Series presents Angela Palm
          March 29 7:30pm
          A native of Indiana, Angela Palm is the author of Riverine: A Memoir from Anywhere but Here, published by Graywolf Press in 2016. She owns Ink + Lead Literary Services and is the editor of an anthology of Vermont writers, Please Do Not Remove. Her work has appeared in Paper Darts, Midwestern Gothic, Tampa Review, and elsewhere. She lives in Burl more »
        Wednesday, March 29, 2017

          About This Event

          Summary

          Abstract: In this talk, I will introduce two new computational problems stemming from the analysis of next-generation sequencing data. In the first, I will describe the problem of determining the position of nucleosomes in a genome (nucleosomes are the basic elements of DNA chromatin structure). We solved this problem using a method based on a modified Gaussian mixture model. An expectation maximization (EM) algorithm is used to infer the parameters of the mixture of distributions.

          In the second, I will briefly address the problem of obtaining the primary sequence for large, complex genomes. We propose a BAC-by-BAC sequencing protocol that leverages recent advances in combinatorial pooling design (group testing). I will show that combinatorial pooling is a cost-effective and practical alternative to exhaustive DNA barcoding when preparing sequencing libraries for hundreds or thousands of DNA samples, such as in this case case gene-bearing BAC clones.

           

          Bio: Stefano Lonardi is Professor and Vice Chair of the Department of Computer Science and Engineering at University of California, Riverside, CA. He is also a faculty member of the Graduate Program in Genetics, Genomics and Bioinformatics, the Center for Plant Cell Biology, the Institute for Integrative Genome Biology, and the Graduate Program in Cell, Molecular and Developmental Biology.

          Stefano received his Laurea cum laude from University of Pisa in 1994 and his Ph.D. in the summer of 2001 from the Department of Computer Sciences, Purdue University, West Lafayette, IN.  He also holds a doctorate degree in Electrical and Information Engineering from University of Padua (1999). During the summer of 1999, he was intern at Celera Genomics, Department of Informatics Research, Rockville, MD.

          Stefano's recent research interest includes design of algorithms, computational molecular biology, data compression and data mining. He has published over 40 papers in major theoretical computer science and computational biology journals and over 50 publications in refereed international conferences. In the year 2005, he received the CAREER award from National Science Foundation. He has received funding from NSF, NIH, DARPA, and USDA.

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          There are no upcoming dates for this event.

          IU Calendar




          • Speedo Champions Series
            March 29 12:00am
            Swim Meet more »
          • Phyllis Bramson | Love and Affection in a Hostile World
            March 29 10:00am
            A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
          • Philip Powell presents Business and the Poor:The Ethics and the Economics
            March 29 7:00pm
            The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
          • Philip Powell presents Business and the Poor:The Ethics and the Economics
            March 29 7:00pm
            The world's economic resources are overwhelming consolidated in business, or markets.  While governments and NGOs have a role to play in economic development and poverty alleviation, the power of business to radically transform the lives of the world's income-poor communities is exponentially greater.  The six-part seminar will more »
          • The Rufus and Louise Reiberg Reading Series presents Angela Palm
            March 29 7:30pm
            A native of Indiana, Angela Palm is the author of Riverine: A Memoir from Anywhere but Here, published by Graywolf Press in 2016. She owns Ink + Lead Literary Services and is the editor of an anthology of Vermont writers, Please Do Not Remove. Her work has appeared in Paper Darts, Midwestern Gothic, Tampa Review, and elsewhere. She lives in Burl more »
          Wednesday, March 29, 2017