• IU Pediatric Dental Alumni Suite
    May 25 12:00am
    For more information please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
  • Competition Pool
    May 25 5:30am
    Lap swim more »
  • IU Simon Cancer Center Summer Research Program Welcome Dinner
    May 25 4:00pm
    The IU Simon Cancer Center Summer Research Program aims to increase the number of undergraduate students from underrepresented populations pursuing biomedical and behavioral science careers by providing positive and meaningful firsthand exposure to these fields.   Tonight is the welcome dinner more »
  • Organizations and Religion; Religion, Spirituality, Healthcare, and Ethics Seminar
    May 25 6:00pm
    Facilitators:  Steven S. Ivy, PhD & David Craig, PhD Dinner and books will be provided free of charge. RSVP to srush7@iuhealth.org by May 11 so we can mail books and plan the meal. PLEASE PROVIDE A MAILING ADDRESS, CAMPUS OR US MAIL.   Readings:  Craig, D.M. (2014). Health care as a social good : religious more »
  • Competition Pool
    May 26 5:30am
    Lap Swim more »
Thursday, May 25, 2017
    IU Calendar




    • IU Pediatric Dental Alumni Suite
      May 25 12:00am
      For more information please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
    • Competition Pool
      May 25 5:30am
      Lap swim more »
    • IU Simon Cancer Center Summer Research Program Welcome Dinner
      May 25 4:00pm
      The IU Simon Cancer Center Summer Research Program aims to increase the number of undergraduate students from underrepresented populations pursuing biomedical and behavioral science careers by providing positive and meaningful firsthand exposure to these fields.   Tonight is the welcome dinner more »
    • Organizations and Religion; Religion, Spirituality, Healthcare, and Ethics Seminar
      May 25 6:00pm
      Facilitators:  Steven S. Ivy, PhD & David Craig, PhD Dinner and books will be provided free of charge. RSVP to srush7@iuhealth.org by May 11 so we can mail books and plan the meal. PLEASE PROVIDE A MAILING ADDRESS, CAMPUS OR US MAIL.   Readings:  Craig, D.M. (2014). Health care as a social good : religious more »
    • Competition Pool
      May 26 5:30am
      Lap Swim more »
    Thursday, May 25, 2017
      IU Calendar




      • IU Pediatric Dental Alumni Suite
        May 25 12:00am
        For more information please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
      • Competition Pool
        May 25 5:30am
        Lap swim more »
      • IU Simon Cancer Center Summer Research Program Welcome Dinner
        May 25 4:00pm
        The IU Simon Cancer Center Summer Research Program aims to increase the number of undergraduate students from underrepresented populations pursuing biomedical and behavioral science careers by providing positive and meaningful firsthand exposure to these fields.   Tonight is the welcome dinner more »
      • Organizations and Religion; Religion, Spirituality, Healthcare, and Ethics Seminar
        May 25 6:00pm
        Facilitators:  Steven S. Ivy, PhD & David Craig, PhD Dinner and books will be provided free of charge. RSVP to srush7@iuhealth.org by May 11 so we can mail books and plan the meal. PLEASE PROVIDE A MAILING ADDRESS, CAMPUS OR US MAIL.   Readings:  Craig, D.M. (2014). Health care as a social good : religious more »
      • Competition Pool
        May 26 5:30am
        Lap Swim more »
      Thursday, May 25, 2017
        IU Calendar




        • IU Pediatric Dental Alumni Suite
          May 25 12:00am
          For more information please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
        • Competition Pool
          May 25 5:30am
          Lap swim more »
        • IU Simon Cancer Center Summer Research Program Welcome Dinner
          May 25 4:00pm
          The IU Simon Cancer Center Summer Research Program aims to increase the number of undergraduate students from underrepresented populations pursuing biomedical and behavioral science careers by providing positive and meaningful firsthand exposure to these fields.   Tonight is the welcome dinner more »
        • Organizations and Religion; Religion, Spirituality, Healthcare, and Ethics Seminar
          May 25 6:00pm
          Facilitators:  Steven S. Ivy, PhD & David Craig, PhD Dinner and books will be provided free of charge. RSVP to srush7@iuhealth.org by May 11 so we can mail books and plan the meal. PLEASE PROVIDE A MAILING ADDRESS, CAMPUS OR US MAIL.   Readings:  Craig, D.M. (2014). Health care as a social good : religious more »
        • Competition Pool
          May 26 5:30am
          Lap Swim more »
        Thursday, May 25, 2017

          About This Event

          Summary

          Abstract: In this talk, I will introduce two new computational problems stemming from the analysis of next-generation sequencing data. In the first, I will describe the problem of determining the position of nucleosomes in a genome (nucleosomes are the basic elements of DNA chromatin structure). We solved this problem using a method based on a modified Gaussian mixture model. An expectation maximization (EM) algorithm is used to infer the parameters of the mixture of distributions.

          In the second, I will briefly address the problem of obtaining the primary sequence for large, complex genomes. We propose a BAC-by-BAC sequencing protocol that leverages recent advances in combinatorial pooling design (group testing). I will show that combinatorial pooling is a cost-effective and practical alternative to exhaustive DNA barcoding when preparing sequencing libraries for hundreds or thousands of DNA samples, such as in this case case gene-bearing BAC clones.

           

          Bio: Stefano Lonardi is Professor and Vice Chair of the Department of Computer Science and Engineering at University of California, Riverside, CA. He is also a faculty member of the Graduate Program in Genetics, Genomics and Bioinformatics, the Center for Plant Cell Biology, the Institute for Integrative Genome Biology, and the Graduate Program in Cell, Molecular and Developmental Biology.

          Stefano received his Laurea cum laude from University of Pisa in 1994 and his Ph.D. in the summer of 2001 from the Department of Computer Sciences, Purdue University, West Lafayette, IN.  He also holds a doctorate degree in Electrical and Information Engineering from University of Padua (1999). During the summer of 1999, he was intern at Celera Genomics, Department of Informatics Research, Rockville, MD.

          Stefano's recent research interest includes design of algorithms, computational molecular biology, data compression and data mining. He has published over 40 papers in major theoretical computer science and computational biology journals and over 50 publications in refereed international conferences. In the year 2005, he received the CAREER award from National Science Foundation. He has received funding from NSF, NIH, DARPA, and USDA.

          Bookmark and Share

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • IU Pediatric Dental Alumni Suite
            May 25 12:00am
            For more information please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
          • Competition Pool
            May 25 5:30am
            Lap swim more »
          • IU Simon Cancer Center Summer Research Program Welcome Dinner
            May 25 4:00pm
            The IU Simon Cancer Center Summer Research Program aims to increase the number of undergraduate students from underrepresented populations pursuing biomedical and behavioral science careers by providing positive and meaningful firsthand exposure to these fields.   Tonight is the welcome dinner more »
          • Organizations and Religion; Religion, Spirituality, Healthcare, and Ethics Seminar
            May 25 6:00pm
            Facilitators:  Steven S. Ivy, PhD & David Craig, PhD Dinner and books will be provided free of charge. RSVP to srush7@iuhealth.org by May 11 so we can mail books and plan the meal. PLEASE PROVIDE A MAILING ADDRESS, CAMPUS OR US MAIL.   Readings:  Craig, D.M. (2014). Health care as a social good : religious more »
          • Competition Pool
            May 26 5:30am
            Lap Swim more »
          Thursday, May 25, 2017