• CLOSED
    December 10 12:00am
    Facility closed more »
  • JAGS Invite
    December 10 12:00am
    Swim meet more »
  • Al-Mutanabbi Street Starts Here
    December 10 10:00am
    A car bomb exploded in 2007 in the historic intellectual center of Baghdad, al-Mutanabbi Street. More than 130 people died or were wounded, but the place escaped geographic bounds to become a global movement for the free exchange of ideas. View selections from a rare collection of artist's books and broadsides that continue to be generated a more »
  • Undergraduate Student Exhibition
    December 10 10:00am
    The Undergraduate Student Exhibition is juried by Liz Garvey of Simon Garvey Art Access Gallery in New York. Works are typically selected from hundreds of submission across a wide variety of media. more »
  • CLOSED
    December 11 12:00am
    The competition lap pool for lap swim is closed. more »
Saturday, December 10, 2016
    IU Calendar




    • CLOSED
      December 10 12:00am
      Facility closed more »
    • JAGS Invite
      December 10 12:00am
      Swim meet more »
    • Al-Mutanabbi Street Starts Here
      December 10 10:00am
      A car bomb exploded in 2007 in the historic intellectual center of Baghdad, al-Mutanabbi Street. More than 130 people died or were wounded, but the place escaped geographic bounds to become a global movement for the free exchange of ideas. View selections from a rare collection of artist's books and broadsides that continue to be generated a more »
    • Undergraduate Student Exhibition
      December 10 10:00am
      The Undergraduate Student Exhibition is juried by Liz Garvey of Simon Garvey Art Access Gallery in New York. Works are typically selected from hundreds of submission across a wide variety of media. more »
    • CLOSED
      December 11 12:00am
      The competition lap pool for lap swim is closed. more »
    Saturday, December 10, 2016
      IU Calendar




      • CLOSED
        December 10 12:00am
        Facility closed more »
      • JAGS Invite
        December 10 12:00am
        Swim meet more »
      • Al-Mutanabbi Street Starts Here
        December 10 10:00am
        A car bomb exploded in 2007 in the historic intellectual center of Baghdad, al-Mutanabbi Street. More than 130 people died or were wounded, but the place escaped geographic bounds to become a global movement for the free exchange of ideas. View selections from a rare collection of artist's books and broadsides that continue to be generated a more »
      • Undergraduate Student Exhibition
        December 10 10:00am
        The Undergraduate Student Exhibition is juried by Liz Garvey of Simon Garvey Art Access Gallery in New York. Works are typically selected from hundreds of submission across a wide variety of media. more »
      • CLOSED
        December 11 12:00am
        The competition lap pool for lap swim is closed. more »
      Saturday, December 10, 2016
        IU Calendar




        • CLOSED
          December 10 12:00am
          Facility closed more »
        • JAGS Invite
          December 10 12:00am
          Swim meet more »
        • Al-Mutanabbi Street Starts Here
          December 10 10:00am
          A car bomb exploded in 2007 in the historic intellectual center of Baghdad, al-Mutanabbi Street. More than 130 people died or were wounded, but the place escaped geographic bounds to become a global movement for the free exchange of ideas. View selections from a rare collection of artist's books and broadsides that continue to be generated a more »
        • Undergraduate Student Exhibition
          December 10 10:00am
          The Undergraduate Student Exhibition is juried by Liz Garvey of Simon Garvey Art Access Gallery in New York. Works are typically selected from hundreds of submission across a wide variety of media. more »
        • CLOSED
          December 11 12:00am
          The competition lap pool for lap swim is closed. more »
        Saturday, December 10, 2016

          About This Event

          Summary

          Abstract: In this talk, I will introduce two new computational problems stemming from the analysis of next-generation sequencing data. In the first, I will describe the problem of determining the position of nucleosomes in a genome (nucleosomes are the basic elements of DNA chromatin structure). We solved this problem using a method based on a modified Gaussian mixture model. An expectation maximization (EM) algorithm is used to infer the parameters of the mixture of distributions.

          In the second, I will briefly address the problem of obtaining the primary sequence for large, complex genomes. We propose a BAC-by-BAC sequencing protocol that leverages recent advances in combinatorial pooling design (group testing). I will show that combinatorial pooling is a cost-effective and practical alternative to exhaustive DNA barcoding when preparing sequencing libraries for hundreds or thousands of DNA samples, such as in this case case gene-bearing BAC clones.

           

          Bio: Stefano Lonardi is Professor and Vice Chair of the Department of Computer Science and Engineering at University of California, Riverside, CA. He is also a faculty member of the Graduate Program in Genetics, Genomics and Bioinformatics, the Center for Plant Cell Biology, the Institute for Integrative Genome Biology, and the Graduate Program in Cell, Molecular and Developmental Biology.

          Stefano received his Laurea cum laude from University of Pisa in 1994 and his Ph.D. in the summer of 2001 from the Department of Computer Sciences, Purdue University, West Lafayette, IN.  He also holds a doctorate degree in Electrical and Information Engineering from University of Padua (1999). During the summer of 1999, he was intern at Celera Genomics, Department of Informatics Research, Rockville, MD.

          Stefano's recent research interest includes design of algorithms, computational molecular biology, data compression and data mining. He has published over 40 papers in major theoretical computer science and computational biology journals and over 50 publications in refereed international conferences. In the year 2005, he received the CAREER award from National Science Foundation. He has received funding from NSF, NIH, DARPA, and USDA.

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          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • CLOSED
            December 10 12:00am
            Facility closed more »
          • JAGS Invite
            December 10 12:00am
            Swim meet more »
          • Al-Mutanabbi Street Starts Here
            December 10 10:00am
            A car bomb exploded in 2007 in the historic intellectual center of Baghdad, al-Mutanabbi Street. More than 130 people died or were wounded, but the place escaped geographic bounds to become a global movement for the free exchange of ideas. View selections from a rare collection of artist's books and broadsides that continue to be generated a more »
          • Undergraduate Student Exhibition
            December 10 10:00am
            The Undergraduate Student Exhibition is juried by Liz Garvey of Simon Garvey Art Access Gallery in New York. Works are typically selected from hundreds of submission across a wide variety of media. more »
          • CLOSED
            December 11 12:00am
            The competition lap pool for lap swim is closed. more »
          Saturday, December 10, 2016