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About This Event


“Exogeneous Estrogenic Hormones, Diethylstilbestrol (DES), Vaginal Adenosis, and Clear Cell Adenocarcinoma in Young Women: A Therapeutic Misadventure”


Lawrence M. Roth, M.D.

Professor Emeritus of Pathology

Indiana University School of Medicine


This presentation is a narrative about diethylstilbestrol (DES) which was

first synthesized in 1938 and prescribed from the 1940s to 1971 to try to

prevent complications of pregnancy. The discovery of unforeseen side

effects in the early 1970s sparked controversies that continue to the

present day.


Dr. Roth, in collaboration with Dr. Ned Hornback, published a

report on the relationship of DES and cervical clear cell adenocarcinoma in young women in 1974 and has maintained a keen interest in the topic since that time.


A pizza lunch will be provided.  Space is limited.  Please RSVP to medhum@iupui.edu.


Part of the John Shaw Billings History of Medicine Society's History of Medicine Speaker Series 2013.  Sponsored by the Indiana University History of Medicine Student Interest Group.  Co-sponsored by the Medical Humanities & Health Studies Program.

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