• JAGS Invite
    December 09 12:00am
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  • 2016 IUPUI Holiday Night for Young Alumni
    December 09 6:30pm
    IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
  • IUPUI Holiday Night
    December 09 6:30pm
    Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
  • CLOSED
    December 10 12:00am
    Facility closed more »
  • JAGS Invite
    December 10 12:00am
    Swim meet more »
Friday, December 9, 2016
    IU Calendar




    • JAGS Invite
      December 09 12:00am
      Swim meet more »
    • 2016 IUPUI Holiday Night for Young Alumni
      December 09 6:30pm
      IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
    • IUPUI Holiday Night
      December 09 6:30pm
      Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
    • CLOSED
      December 10 12:00am
      Facility closed more »
    • JAGS Invite
      December 10 12:00am
      Swim meet more »
    Friday, December 9, 2016
      IU Calendar




      • JAGS Invite
        December 09 12:00am
        Swim meet more »
      • 2016 IUPUI Holiday Night for Young Alumni
        December 09 6:30pm
        IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
      • IUPUI Holiday Night
        December 09 6:30pm
        Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
      • CLOSED
        December 10 12:00am
        Facility closed more »
      • JAGS Invite
        December 10 12:00am
        Swim meet more »
      Friday, December 9, 2016
        IU Calendar




        • JAGS Invite
          December 09 12:00am
          Swim meet more »
        • 2016 IUPUI Holiday Night for Young Alumni
          December 09 6:30pm
          IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
        • IUPUI Holiday Night
          December 09 6:30pm
          Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
        • CLOSED
          December 10 12:00am
          Facility closed more »
        • JAGS Invite
          December 10 12:00am
          Swim meet more »
        Friday, December 9, 2016

          About This Event

          Summary

          Announcing the Final Examination of Huiying Zhao for the Degree of Doctor of Philosophy in informatics

          Dissertation: Protein function prediction by integrating sequence, structure and binding affinity information

          Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to be annotated because inexpensive sequencing techniques dramatically speed up discovery of new protein sequences (265 million and counting) and experimental examinations of every protein in all its possible functional categories are simply impractical. Thus, it is necessary to develop computational function-prediction tools that complement and guide experimental studies. In this study, we developed a series of predictors for highly accurate prediction of proteins with DNA-binding, RNA-binding and carbohydrate-binding capability. These predictors are a template-based technique that combines sequence and structural information with predicted binding affinity. Both sequence and structure-based approaches were developed. Results indicate the importance of binding affinity prediction for improving sensitivity and precision of function prediction. Application of these methods to the human genome and structure genome targets demonstrated its usefulness in annotating proteins of unknown functions and discovering moon-lighting proteins with DNA, RNA, or carbohydrate binding function. The predictors are available at http://sparks.informatics.iupui.edu/spot.

          Education Career 

          • Major: Bioinformatics BS, North China University, 2001

          • Minor(s): Biostatistics 

          Committee in Charge

          • Yunlong Liu, PhD, Chairman, 317-278-9222

          • Yaoqi Zhou, PhD, Advisor

          • Samy Meroueh‎, PhD

          • Sarath Chandra Janga, PhD

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          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • JAGS Invite
            December 09 12:00am
            Swim meet more »
          • 2016 IUPUI Holiday Night for Young Alumni
            December 09 6:30pm
            IUPUI invites those young alumni who want to toast to sleigh rides, family and friends, festive lights, childhood wonder, mistletoe, roasted chestnuts, and the most wonderful time of the year to Holiday Night. This special event includes a tour of the Children’s Museum private toy collection, a cash bar with a complimentary drink ticket fo more »
          • IUPUI Holiday Night
            December 09 6:30pm
            Bring the little ones, or just yourself, to the Indianapolis Children's Museum on Friday, December 9 from 6:30 p.m. to 9:00 p.m. for holiday cheer and music, good food, Santa, the popular Jolly Slide, and carousel rides. Visit all five floors of the museum after-hours without the crowds, interact with our IUPUI affiliates, and children ages more »
          • CLOSED
            December 10 12:00am
            Facility closed more »
          • JAGS Invite
            December 10 12:00am
            Swim meet more »
          Friday, December 9, 2016