• Competition Pool
    April 25 5:30am
    Lap Swim more »
  • Kindness Week: Conversation Hour: Chai Time with International Students
    April 25 1:00pm
    Introducing. . .Chai Time with International Students! Join us for a conversation hour about the role of international writing consultants in the Writing Center, faciliated by some of our international consultants, in CA 427. Arabic Chai, Arabic coffee, cookies, German cookies will be provided. Kindness Week is brought to you by the IUPUI U more »
  • Kindness Week: "Broken Places" reading by Kelin Hull
    April 25 5:00pm
    Join us in CA 427 for a reading of "Broken Places," a narrative piece by UWC consultant and beacon of kindness Kelin Hull! Kindness Week is brought to you by the IUPUI University Writing Center. more »
  • IU Baseball vs. Ball State at Victory Field
    April 25 7:00pm
    Help us cheer on the Hoosiers as the IU baseball team takes on Ball State at Victory Field on April 25. The Central Indiana Chapter is offering reserved tickets in a special section right behind the IU dugout. Tickets are $5 for IUAA members and $10 for nonmembers. All kids’ tickets are $5. The game starts at 7 pm. All are welcome to a more »
  • IUPUI Department of Music and Arts Technology - Jazz Combo/Electric Guitar Ensemble
    April 25 7:30pm
    Jazz Combo/Electric Guitar Ensemble more »
Tuesday, April 25, 2017
    IU Calendar




    • Competition Pool
      April 25 5:30am
      Lap Swim more »
    • Kindness Week: Conversation Hour: Chai Time with International Students
      April 25 1:00pm
      Introducing. . .Chai Time with International Students! Join us for a conversation hour about the role of international writing consultants in the Writing Center, faciliated by some of our international consultants, in CA 427. Arabic Chai, Arabic coffee, cookies, German cookies will be provided. Kindness Week is brought to you by the IUPUI U more »
    • Kindness Week: "Broken Places" reading by Kelin Hull
      April 25 5:00pm
      Join us in CA 427 for a reading of "Broken Places," a narrative piece by UWC consultant and beacon of kindness Kelin Hull! Kindness Week is brought to you by the IUPUI University Writing Center. more »
    • IU Baseball vs. Ball State at Victory Field
      April 25 7:00pm
      Help us cheer on the Hoosiers as the IU baseball team takes on Ball State at Victory Field on April 25. The Central Indiana Chapter is offering reserved tickets in a special section right behind the IU dugout. Tickets are $5 for IUAA members and $10 for nonmembers. All kids’ tickets are $5. The game starts at 7 pm. All are welcome to a more »
    • IUPUI Department of Music and Arts Technology - Jazz Combo/Electric Guitar Ensemble
      April 25 7:30pm
      Jazz Combo/Electric Guitar Ensemble more »
    Tuesday, April 25, 2017
      IU Calendar




      • Competition Pool
        April 25 5:30am
        Lap Swim more »
      • Kindness Week: Conversation Hour: Chai Time with International Students
        April 25 1:00pm
        Introducing. . .Chai Time with International Students! Join us for a conversation hour about the role of international writing consultants in the Writing Center, faciliated by some of our international consultants, in CA 427. Arabic Chai, Arabic coffee, cookies, German cookies will be provided. Kindness Week is brought to you by the IUPUI U more »
      • Kindness Week: "Broken Places" reading by Kelin Hull
        April 25 5:00pm
        Join us in CA 427 for a reading of "Broken Places," a narrative piece by UWC consultant and beacon of kindness Kelin Hull! Kindness Week is brought to you by the IUPUI University Writing Center. more »
      • IU Baseball vs. Ball State at Victory Field
        April 25 7:00pm
        Help us cheer on the Hoosiers as the IU baseball team takes on Ball State at Victory Field on April 25. The Central Indiana Chapter is offering reserved tickets in a special section right behind the IU dugout. Tickets are $5 for IUAA members and $10 for nonmembers. All kids’ tickets are $5. The game starts at 7 pm. All are welcome to a more »
      • IUPUI Department of Music and Arts Technology - Jazz Combo/Electric Guitar Ensemble
        April 25 7:30pm
        Jazz Combo/Electric Guitar Ensemble more »
      Tuesday, April 25, 2017
        IU Calendar




        • Competition Pool
          April 25 5:30am
          Lap Swim more »
        • Kindness Week: Conversation Hour: Chai Time with International Students
          April 25 1:00pm
          Introducing. . .Chai Time with International Students! Join us for a conversation hour about the role of international writing consultants in the Writing Center, faciliated by some of our international consultants, in CA 427. Arabic Chai, Arabic coffee, cookies, German cookies will be provided. Kindness Week is brought to you by the IUPUI U more »
        • Kindness Week: "Broken Places" reading by Kelin Hull
          April 25 5:00pm
          Join us in CA 427 for a reading of "Broken Places," a narrative piece by UWC consultant and beacon of kindness Kelin Hull! Kindness Week is brought to you by the IUPUI University Writing Center. more »
        • IU Baseball vs. Ball State at Victory Field
          April 25 7:00pm
          Help us cheer on the Hoosiers as the IU baseball team takes on Ball State at Victory Field on April 25. The Central Indiana Chapter is offering reserved tickets in a special section right behind the IU dugout. Tickets are $5 for IUAA members and $10 for nonmembers. All kids’ tickets are $5. The game starts at 7 pm. All are welcome to a more »
        • IUPUI Department of Music and Arts Technology - Jazz Combo/Electric Guitar Ensemble
          April 25 7:30pm
          Jazz Combo/Electric Guitar Ensemble more »
        Tuesday, April 25, 2017

          About This Event

          Summary

          Announcing the Final Examination of Huiying Zhao for the Degree of Doctor of Philosophy in informatics

          Dissertation: Protein function prediction by integrating sequence, structure and binding affinity information

          Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to be annotated because inexpensive sequencing techniques dramatically speed up discovery of new protein sequences (265 million and counting) and experimental examinations of every protein in all its possible functional categories are simply impractical. Thus, it is necessary to develop computational function-prediction tools that complement and guide experimental studies. In this study, we developed a series of predictors for highly accurate prediction of proteins with DNA-binding, RNA-binding and carbohydrate-binding capability. These predictors are a template-based technique that combines sequence and structural information with predicted binding affinity. Both sequence and structure-based approaches were developed. Results indicate the importance of binding affinity prediction for improving sensitivity and precision of function prediction. Application of these methods to the human genome and structure genome targets demonstrated its usefulness in annotating proteins of unknown functions and discovering moon-lighting proteins with DNA, RNA, or carbohydrate binding function. The predictors are available at http://sparks.informatics.iupui.edu/spot.

          Education Career 

          • Major: Bioinformatics BS, North China University, 2001

          • Minor(s): Biostatistics 

          Committee in Charge

          • Yunlong Liu, PhD, Chairman, 317-278-9222

          • Yaoqi Zhou, PhD, Advisor

          • Samy Meroueh‎, PhD

          • Sarath Chandra Janga, PhD

          Bookmark and Share
          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • Competition Pool
            April 25 5:30am
            Lap Swim more »
          • Kindness Week: Conversation Hour: Chai Time with International Students
            April 25 1:00pm
            Introducing. . .Chai Time with International Students! Join us for a conversation hour about the role of international writing consultants in the Writing Center, faciliated by some of our international consultants, in CA 427. Arabic Chai, Arabic coffee, cookies, German cookies will be provided. Kindness Week is brought to you by the IUPUI U more »
          • Kindness Week: "Broken Places" reading by Kelin Hull
            April 25 5:00pm
            Join us in CA 427 for a reading of "Broken Places," a narrative piece by UWC consultant and beacon of kindness Kelin Hull! Kindness Week is brought to you by the IUPUI University Writing Center. more »
          • IU Baseball vs. Ball State at Victory Field
            April 25 7:00pm
            Help us cheer on the Hoosiers as the IU baseball team takes on Ball State at Victory Field on April 25. The Central Indiana Chapter is offering reserved tickets in a special section right behind the IU dugout. Tickets are $5 for IUAA members and $10 for nonmembers. All kids’ tickets are $5. The game starts at 7 pm. All are welcome to a more »
          • IUPUI Department of Music and Arts Technology - Jazz Combo/Electric Guitar Ensemble
            April 25 7:30pm
            Jazz Combo/Electric Guitar Ensemble more »
          Tuesday, April 25, 2017