• CLOSED
    June 28 12:00am
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  • USA Swimming National Championships
    June 28 12:00am
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  • Nanotechnology Experiences for Students and Teachers
    June 29 8:45am
    High School students, grades 9-12, come for 2 weeks of programming that explore the interdisciplinary field of nanotechnology.  This cutting-edge field is rapidly becoming an essential part of science, engineering, medicine, and many other disciplines.  They will earn a college credit hour in Engineering & Technology and/or Sc more »
  • SQL: Advanced Data Retrieval and Data Modification
    June 29 1:30pm
    This workshop lasts 3 hours. Building on what was covered in SQL: Data Retrieval, this workshop is intended for anyone wants to learn how to use SQL to add, update, and delete data and learn advanced data retrieval techniques. In addition, participants will learn basic concepts of database transaction processing. more »
  • Mindfulness Meditation
    June 30 11:00am
    Feeling stressed and overwhelmed? Looking for an opportunity to practice self-care? Join us for guided mindfulness meditation. You don't have to be a CAPS client and no registration is needed. Student ID is required. more »
Wednesday, June 28, 2017
    IU Calendar




    • CLOSED
      June 28 12:00am
      pool closed more »
    • USA Swimming National Championships
      June 28 12:00am
      meet more »
    • Nanotechnology Experiences for Students and Teachers
      June 29 8:45am
      High School students, grades 9-12, come for 2 weeks of programming that explore the interdisciplinary field of nanotechnology.  This cutting-edge field is rapidly becoming an essential part of science, engineering, medicine, and many other disciplines.  They will earn a college credit hour in Engineering & Technology and/or Sc more »
    • SQL: Advanced Data Retrieval and Data Modification
      June 29 1:30pm
      This workshop lasts 3 hours. Building on what was covered in SQL: Data Retrieval, this workshop is intended for anyone wants to learn how to use SQL to add, update, and delete data and learn advanced data retrieval techniques. In addition, participants will learn basic concepts of database transaction processing. more »
    • Mindfulness Meditation
      June 30 11:00am
      Feeling stressed and overwhelmed? Looking for an opportunity to practice self-care? Join us for guided mindfulness meditation. You don't have to be a CAPS client and no registration is needed. Student ID is required. more »
    Wednesday, June 28, 2017
      IU Calendar




      • CLOSED
        June 28 12:00am
        pool closed more »
      • USA Swimming National Championships
        June 28 12:00am
        meet more »
      • Nanotechnology Experiences for Students and Teachers
        June 29 8:45am
        High School students, grades 9-12, come for 2 weeks of programming that explore the interdisciplinary field of nanotechnology.  This cutting-edge field is rapidly becoming an essential part of science, engineering, medicine, and many other disciplines.  They will earn a college credit hour in Engineering & Technology and/or Sc more »
      • SQL: Advanced Data Retrieval and Data Modification
        June 29 1:30pm
        This workshop lasts 3 hours. Building on what was covered in SQL: Data Retrieval, this workshop is intended for anyone wants to learn how to use SQL to add, update, and delete data and learn advanced data retrieval techniques. In addition, participants will learn basic concepts of database transaction processing. more »
      • Mindfulness Meditation
        June 30 11:00am
        Feeling stressed and overwhelmed? Looking for an opportunity to practice self-care? Join us for guided mindfulness meditation. You don't have to be a CAPS client and no registration is needed. Student ID is required. more »
      Wednesday, June 28, 2017
        IU Calendar




        • CLOSED
          June 28 12:00am
          pool closed more »
        • USA Swimming National Championships
          June 28 12:00am
          meet more »
        • Nanotechnology Experiences for Students and Teachers
          June 29 8:45am
          High School students, grades 9-12, come for 2 weeks of programming that explore the interdisciplinary field of nanotechnology.  This cutting-edge field is rapidly becoming an essential part of science, engineering, medicine, and many other disciplines.  They will earn a college credit hour in Engineering & Technology and/or Sc more »
        • SQL: Advanced Data Retrieval and Data Modification
          June 29 1:30pm
          This workshop lasts 3 hours. Building on what was covered in SQL: Data Retrieval, this workshop is intended for anyone wants to learn how to use SQL to add, update, and delete data and learn advanced data retrieval techniques. In addition, participants will learn basic concepts of database transaction processing. more »
        • Mindfulness Meditation
          June 30 11:00am
          Feeling stressed and overwhelmed? Looking for an opportunity to practice self-care? Join us for guided mindfulness meditation. You don't have to be a CAPS client and no registration is needed. Student ID is required. more »
        Wednesday, June 28, 2017

          About This Event

          Summary

          Announcing the Final Examination of Huiying Zhao for the Degree of Doctor of Philosophy in informatics

          Dissertation: Protein function prediction by integrating sequence, structure and binding affinity information

          Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to be annotated because inexpensive sequencing techniques dramatically speed up discovery of new protein sequences (265 million and counting) and experimental examinations of every protein in all its possible functional categories are simply impractical. Thus, it is necessary to develop computational function-prediction tools that complement and guide experimental studies. In this study, we developed a series of predictors for highly accurate prediction of proteins with DNA-binding, RNA-binding and carbohydrate-binding capability. These predictors are a template-based technique that combines sequence and structural information with predicted binding affinity. Both sequence and structure-based approaches were developed. Results indicate the importance of binding affinity prediction for improving sensitivity and precision of function prediction. Application of these methods to the human genome and structure genome targets demonstrated its usefulness in annotating proteins of unknown functions and discovering moon-lighting proteins with DNA, RNA, or carbohydrate binding function. The predictors are available at http://sparks.informatics.iupui.edu/spot.

          Education Career 

          • Major: Bioinformatics BS, North China University, 2001

          • Minor(s): Biostatistics 

          Committee in Charge

          • Yunlong Liu, PhD, Chairman, 317-278-9222

          • Yaoqi Zhou, PhD, Advisor

          • Samy Meroueh‎, PhD

          • Sarath Chandra Janga, PhD

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          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • CLOSED
            June 28 12:00am
            pool closed more »
          • USA Swimming National Championships
            June 28 12:00am
            meet more »
          • Nanotechnology Experiences for Students and Teachers
            June 29 8:45am
            High School students, grades 9-12, come for 2 weeks of programming that explore the interdisciplinary field of nanotechnology.  This cutting-edge field is rapidly becoming an essential part of science, engineering, medicine, and many other disciplines.  They will earn a college credit hour in Engineering & Technology and/or Sc more »
          • SQL: Advanced Data Retrieval and Data Modification
            June 29 1:30pm
            This workshop lasts 3 hours. Building on what was covered in SQL: Data Retrieval, this workshop is intended for anyone wants to learn how to use SQL to add, update, and delete data and learn advanced data retrieval techniques. In addition, participants will learn basic concepts of database transaction processing. more »
          • Mindfulness Meditation
            June 30 11:00am
            Feeling stressed and overwhelmed? Looking for an opportunity to practice self-care? Join us for guided mindfulness meditation. You don't have to be a CAPS client and no registration is needed. Student ID is required. more »
          Wednesday, June 28, 2017