• CLOSED
    February 26 12:00am
    The competition lap pool for lap swim is closed. more »
  • Limited 50m lanes available
    February 27 12:00am
    lap swim more »
  • American English for International Professionals - Deadline May 31st!
    February 27 12:00am
    ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
  • Competition Pool
    February 27 5:30am
    lap swim more »
  • Freya Powell | Omniscience and Oblivion
    February 27 10:00am
    For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
Sunday, February 26, 2017
    IU Calendar




    • CLOSED
      February 26 12:00am
      The competition lap pool for lap swim is closed. more »
    • Limited 50m lanes available
      February 27 12:00am
      lap swim more »
    • American English for International Professionals - Deadline May 31st!
      February 27 12:00am
      ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
    • Competition Pool
      February 27 5:30am
      lap swim more »
    • Freya Powell | Omniscience and Oblivion
      February 27 10:00am
      For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
    Sunday, February 26, 2017
      IU Calendar




      • CLOSED
        February 26 12:00am
        The competition lap pool for lap swim is closed. more »
      • Limited 50m lanes available
        February 27 12:00am
        lap swim more »
      • American English for International Professionals - Deadline May 31st!
        February 27 12:00am
        ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
      • Competition Pool
        February 27 5:30am
        lap swim more »
      • Freya Powell | Omniscience and Oblivion
        February 27 10:00am
        For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
      Sunday, February 26, 2017
        IU Calendar




        • CLOSED
          February 26 12:00am
          The competition lap pool for lap swim is closed. more »
        • Limited 50m lanes available
          February 27 12:00am
          lap swim more »
        • American English for International Professionals - Deadline May 31st!
          February 27 12:00am
          ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
        • Competition Pool
          February 27 5:30am
          lap swim more »
        • Freya Powell | Omniscience and Oblivion
          February 27 10:00am
          For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
        Sunday, February 26, 2017

          About This Event

          Summary

          Announcing the Final Examination of Huiying Zhao for the Degree of Doctor of Philosophy in informatics

          Dissertation: Protein function prediction by integrating sequence, structure and binding affinity information

          Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to be annotated because inexpensive sequencing techniques dramatically speed up discovery of new protein sequences (265 million and counting) and experimental examinations of every protein in all its possible functional categories are simply impractical. Thus, it is necessary to develop computational function-prediction tools that complement and guide experimental studies. In this study, we developed a series of predictors for highly accurate prediction of proteins with DNA-binding, RNA-binding and carbohydrate-binding capability. These predictors are a template-based technique that combines sequence and structural information with predicted binding affinity. Both sequence and structure-based approaches were developed. Results indicate the importance of binding affinity prediction for improving sensitivity and precision of function prediction. Application of these methods to the human genome and structure genome targets demonstrated its usefulness in annotating proteins of unknown functions and discovering moon-lighting proteins with DNA, RNA, or carbohydrate binding function. The predictors are available at http://sparks.informatics.iupui.edu/spot.

          Education Career 

          • Major: Bioinformatics BS, North China University, 2001

          • Minor(s): Biostatistics 

          Committee in Charge

          • Yunlong Liu, PhD, Chairman, 317-278-9222

          • Yaoqi Zhou, PhD, Advisor

          • Samy Meroueh‎, PhD

          • Sarath Chandra Janga, PhD

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          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • CLOSED
            February 26 12:00am
            The competition lap pool for lap swim is closed. more »
          • Limited 50m lanes available
            February 27 12:00am
            lap swim more »
          • American English for International Professionals - Deadline May 31st!
            February 27 12:00am
            ANNOUNCING THE NEXT AEI COURSE FOR INTERNATIONAL FACULTY, POSTDOCS, FELLOWS, RESIDENTS, MEDICAL STUDENTS AND NURSES:   A personalized program to enhance communication skills through accent modification March 22– May 31, 2017   The mission of AEI is to help international medical professionals empower themse more »
          • Competition Pool
            February 27 5:30am
            lap swim more »
          • Freya Powell | Omniscience and Oblivion
            February 27 10:00am
            For this sound installation, New York-based artist Freya Powell created an audio archive where participants were invited to anonymously share one memory they would like to keep forever and one they would like to let go. more »
          Sunday, February 26, 2017