• CLOSED
    August 19 12:00am
    Closed more »
  • IU School of Public Health Alumni Board Meeting
    August 19 4:30pm
    For additional information, please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
  • 2017 IUPUI and IU Symphony on the Prairie
    August 19 6:00pm
    Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
  • IU Lilly School of Philanthropy Symphony on the Prairie
    August 19 6:30pm
    Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
  • IU School of Public Health Night at Conner Prairie
    August 19 6:30pm
    Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
Saturday, August 19, 2017
    IU Calendar




    • CLOSED
      August 19 12:00am
      Closed more »
    • IU School of Public Health Alumni Board Meeting
      August 19 4:30pm
      For additional information, please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
    • 2017 IUPUI and IU Symphony on the Prairie
      August 19 6:00pm
      Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
    • IU Lilly School of Philanthropy Symphony on the Prairie
      August 19 6:30pm
      Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
    • IU School of Public Health Night at Conner Prairie
      August 19 6:30pm
      Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
    Saturday, August 19, 2017
      IU Calendar




      • CLOSED
        August 19 12:00am
        Closed more »
      • IU School of Public Health Alumni Board Meeting
        August 19 4:30pm
        For additional information, please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
      • 2017 IUPUI and IU Symphony on the Prairie
        August 19 6:00pm
        Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
      • IU Lilly School of Philanthropy Symphony on the Prairie
        August 19 6:30pm
        Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
      • IU School of Public Health Night at Conner Prairie
        August 19 6:30pm
        Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
      Saturday, August 19, 2017
        IU Calendar




        • CLOSED
          August 19 12:00am
          Closed more »
        • IU School of Public Health Alumni Board Meeting
          August 19 4:30pm
          For additional information, please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
        • 2017 IUPUI and IU Symphony on the Prairie
          August 19 6:00pm
          Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
        • IU Lilly School of Philanthropy Symphony on the Prairie
          August 19 6:30pm
          Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
        • IU School of Public Health Night at Conner Prairie
          August 19 6:30pm
          Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
        Saturday, August 19, 2017

          About This Event

          Summary

          Announcing the Final Examination of Huiying Zhao for the Degree of Doctor of Philosophy in informatics

          Dissertation: Protein function prediction by integrating sequence, structure and binding affinity information

          Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to be annotated because inexpensive sequencing techniques dramatically speed up discovery of new protein sequences (265 million and counting) and experimental examinations of every protein in all its possible functional categories are simply impractical. Thus, it is necessary to develop computational function-prediction tools that complement and guide experimental studies. In this study, we developed a series of predictors for highly accurate prediction of proteins with DNA-binding, RNA-binding and carbohydrate-binding capability. These predictors are a template-based technique that combines sequence and structural information with predicted binding affinity. Both sequence and structure-based approaches were developed. Results indicate the importance of binding affinity prediction for improving sensitivity and precision of function prediction. Application of these methods to the human genome and structure genome targets demonstrated its usefulness in annotating proteins of unknown functions and discovering moon-lighting proteins with DNA, RNA, or carbohydrate binding function. The predictors are available at http://sparks.informatics.iupui.edu/spot.

          Education Career 

          • Major: Bioinformatics BS, North China University, 2001

          • Minor(s): Biostatistics 

          Committee in Charge

          • Yunlong Liu, PhD, Chairman, 317-278-9222

          • Yaoqi Zhou, PhD, Advisor

          • Samy Meroueh‎, PhD

          • Sarath Chandra Janga, PhD

          Bookmark and Share
          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • CLOSED
            August 19 12:00am
            Closed more »
          • IU School of Public Health Alumni Board Meeting
            August 19 4:30pm
            For additional information, please contact Karen Jones at kdeery@iupui.edu or 317-274-8959. more »
          • 2017 IUPUI and IU Symphony on the Prairie
            August 19 6:00pm
            Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
          • IU Lilly School of Philanthropy Symphony on the Prairie
            August 19 6:30pm
            Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
          • IU School of Public Health Night at Conner Prairie
            August 19 6:30pm
            Summer in Indianapolis isn't complete without an alumni trip to Symphony on the Prairie. Join other IUPUI and IU alumni from across Central Indiana on August 19 for the music of Fleetwood Mac. The Central Indiana Chapter of the IU Alumni Association will again host a wine tasting with proceeds benefiting the Diabetes Youth Foundation of Indi more »
          Saturday, August 19, 2017