• CLD Success Prep
    October 21 8:00am
    Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
  • Homecoming: Day of Caring
    October 21 8:00am
    Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
  • IUPUI United Way Day of Caring
    October 21 9:00am
    Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
  • Homecoming: NPHC Step Show
    October 21 6:30pm
    As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
  • CLOSED
    October 22 12:00am
    The competition lap pool for lap swim is closed. more »
Saturday, October 21, 2017
    IU Calendar




    • CLD Success Prep
      October 21 8:00am
      Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
    • Homecoming: Day of Caring
      October 21 8:00am
      Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
    • IUPUI United Way Day of Caring
      October 21 9:00am
      Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
    • Homecoming: NPHC Step Show
      October 21 6:30pm
      As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
    • CLOSED
      October 22 12:00am
      The competition lap pool for lap swim is closed. more »
    Saturday, October 21, 2017
      IU Calendar




      • CLD Success Prep
        October 21 8:00am
        Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
      • Homecoming: Day of Caring
        October 21 8:00am
        Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
      • IUPUI United Way Day of Caring
        October 21 9:00am
        Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
      • Homecoming: NPHC Step Show
        October 21 6:30pm
        As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
      • CLOSED
        October 22 12:00am
        The competition lap pool for lap swim is closed. more »
      Saturday, October 21, 2017
        IU Calendar




        • CLD Success Prep
          October 21 8:00am
          Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
        • Homecoming: Day of Caring
          October 21 8:00am
          Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
        • IUPUI United Way Day of Caring
          October 21 9:00am
          Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
        • Homecoming: NPHC Step Show
          October 21 6:30pm
          As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
        • CLOSED
          October 22 12:00am
          The competition lap pool for lap swim is closed. more »
        Saturday, October 21, 2017

          About This Event

          Summary

          Announcing the Final Examination of Huiying Zhao for the Degree of Doctor of Philosophy in informatics

          Dissertation: Protein function prediction by integrating sequence, structure and binding affinity information

          Proteins are nano-machines that work inside every living organism. Functional disruption of one or several proteins is the cause for many diseases. However, the functions for most proteins are yet to be annotated because inexpensive sequencing techniques dramatically speed up discovery of new protein sequences (265 million and counting) and experimental examinations of every protein in all its possible functional categories are simply impractical. Thus, it is necessary to develop computational function-prediction tools that complement and guide experimental studies. In this study, we developed a series of predictors for highly accurate prediction of proteins with DNA-binding, RNA-binding and carbohydrate-binding capability. These predictors are a template-based technique that combines sequence and structural information with predicted binding affinity. Both sequence and structure-based approaches were developed. Results indicate the importance of binding affinity prediction for improving sensitivity and precision of function prediction. Application of these methods to the human genome and structure genome targets demonstrated its usefulness in annotating proteins of unknown functions and discovering moon-lighting proteins with DNA, RNA, or carbohydrate binding function. The predictors are available at http://sparks.informatics.iupui.edu/spot.

          Education Career 

          • Major: Bioinformatics BS, North China University, 2001

          • Minor(s): Biostatistics 

          Committee in Charge

          • Yunlong Liu, PhD, Chairman, 317-278-9222

          • Yaoqi Zhou, PhD, Advisor

          • Samy Meroueh‎, PhD

          • Sarath Chandra Janga, PhD

          Bookmark and Share
          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • CLD Success Prep
            October 21 8:00am
            Success Prep is a high school readiness program intended to give entering freshman the opportunity to have a fresh start.  Over the course of 4 consecutive Saturdays, students and parents gain benefician information regarding the academic, behavioral and social expectations of a successful high school student. more »
          • Homecoming: Day of Caring
            October 21 8:00am
            Connect. Community. Care.  IUPUI United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organiz more »
          • IUPUI United Way Day of Caring
            October 21 9:00am
            Connect. Community. Care.  United Way Day of Caring is an opportunity for you to connect with our Indianapolis community to show that you care. Each fall, IUPUI partners with United Way to host Day of Caring to engage students, faculty, and staff in service with our Indianapolis community. Volunteers impact many non-profit organizations more »
          • Homecoming: NPHC Step Show
            October 21 6:30pm
            As part of the kickoff to Homecoming Week, National Pan-Hellenic Council organizations are hosting a step show. Come watch the show, meet Homecoming Court, and learn more about the week's activities more »
          • CLOSED
            October 22 12:00am
            The competition lap pool for lap swim is closed. more »
          Saturday, October 21, 2017