• Speedo Champions Series
    March 30 12:00am
    Swim Meet more »
  • CLOSED
    March 30 12:00am
    Swim Meet more »
  • Phyllis Bramson | Love and Affection in a Hostile World
    March 30 10:00am
    A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
  • HTML5 & CSS: Structuring Pages
    March 30 1:00pm
    This session is being delivered online and simultaneously in room 144 in Wells Library in Bloomington. This is the online session, so please register for this session only if you plan to attend remotely. This workshop lasts 3.5 hours, more »
  • Developing Complex, Multi-Investigator, Multi-Institutional Proposals
    March 30 4:00pm
    The current funding environment favors large, complex, multi-institutional, multi-investigator projects. However, organizing a successful submission takes a great deal of planning and teamwork. This session will focus on exploring the distinctions between “standard” and “complex” submissions, navigating through issues of more »
Thursday, March 30, 2017
    IU Calendar




    • Speedo Champions Series
      March 30 12:00am
      Swim Meet more »
    • CLOSED
      March 30 12:00am
      Swim Meet more »
    • Phyllis Bramson | Love and Affection in a Hostile World
      March 30 10:00am
      A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
    • HTML5 & CSS: Structuring Pages
      March 30 1:00pm
      This session is being delivered online and simultaneously in room 144 in Wells Library in Bloomington. This is the online session, so please register for this session only if you plan to attend remotely. This workshop lasts 3.5 hours, more »
    • Developing Complex, Multi-Investigator, Multi-Institutional Proposals
      March 30 4:00pm
      The current funding environment favors large, complex, multi-institutional, multi-investigator projects. However, organizing a successful submission takes a great deal of planning and teamwork. This session will focus on exploring the distinctions between “standard” and “complex” submissions, navigating through issues of more »
    Thursday, March 30, 2017
      IU Calendar




      • Speedo Champions Series
        March 30 12:00am
        Swim Meet more »
      • CLOSED
        March 30 12:00am
        Swim Meet more »
      • Phyllis Bramson | Love and Affection in a Hostile World
        March 30 10:00am
        A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
      • HTML5 & CSS: Structuring Pages
        March 30 1:00pm
        This session is being delivered online and simultaneously in room 144 in Wells Library in Bloomington. This is the online session, so please register for this session only if you plan to attend remotely. This workshop lasts 3.5 hours, more »
      • Developing Complex, Multi-Investigator, Multi-Institutional Proposals
        March 30 4:00pm
        The current funding environment favors large, complex, multi-institutional, multi-investigator projects. However, organizing a successful submission takes a great deal of planning and teamwork. This session will focus on exploring the distinctions between “standard” and “complex” submissions, navigating through issues of more »
      Thursday, March 30, 2017
        IU Calendar




        • Speedo Champions Series
          March 30 12:00am
          Swim Meet more »
        • CLOSED
          March 30 12:00am
          Swim Meet more »
        • Phyllis Bramson | Love and Affection in a Hostile World
          March 30 10:00am
          A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
        • HTML5 & CSS: Structuring Pages
          March 30 1:00pm
          This session is being delivered online and simultaneously in room 144 in Wells Library in Bloomington. This is the online session, so please register for this session only if you plan to attend remotely. This workshop lasts 3.5 hours, more »
        • Developing Complex, Multi-Investigator, Multi-Institutional Proposals
          March 30 4:00pm
          The current funding environment favors large, complex, multi-institutional, multi-investigator projects. However, organizing a successful submission takes a great deal of planning and teamwork. This session will focus on exploring the distinctions between “standard” and “complex” submissions, navigating through issues of more »
        Thursday, March 30, 2017

          About This Event

          Summary

          Yogesh Pandit, Master’s in Bioinformatics Thesis Defense

          Title: Context Specific Text Mining For Annotating Protein Interactions With Experimental Evidence

          Thesis committee:

          • Mathew Palakal, Ph.D., Chair

          • Yunlong Liu, Ph.D.

          • Xiaowen Liu, Ph.D.

          Abstract:

          Proteins are the building blocks in a biological system. They interact with other proteins to make unique biological phenomenon. Protein-protein interactions play a valuable role in understanding the molecular mechanisms occurring in any biological system. Protein interaction databases are a rich source on protein interaction related information. They gather large amounts of information from published literature to enrich their data. Expert curators put in most of these efforts manually. The amount of accessible and publicly available literature is growing very rapidly. Manual annotation is a time consuming process. And with the rate at which available information is growing, it cannot be dealt with only manual curation. There need to be tools to process this huge amounts of data to bring out valuable gist than can help curators proceed faster. In case of extracting protein-protein interaction evidences from literature, just a mere mention of a certain protein by look-up approaches cannot help validate the interaction. Supporting protein interaction information with experimental evidence can help this cause. Also to avoid redundancy in curation efforts and for ease of accessibility, efforts are being put to relate manually curated information to standardized ontologies. In this study, we are applying machine learning based classification techniques to classify any given protein interaction related document into an interaction detection method. We use biological attributes and experimental factors, different combination of which define any particular interaction detection method. Then using predicted detection methods, proteins identified using named entity recognition techniques and decomposing the parts-of-speech composition we search for sentences with experimental evidence for a protein-protein interaction. We report an accuracy of 75.1% with a F-score of 47.6% on a dataset containing 2035 training documents and 300 test documents.

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          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • Speedo Champions Series
            March 30 12:00am
            Swim Meet more »
          • CLOSED
            March 30 12:00am
            Swim Meet more »
          • Phyllis Bramson | Love and Affection in a Hostile World
            March 30 10:00am
            A survey of Chicago-based artist Phyllis Bramson's provocative painting and mixed-media work, which examine Eastern iconography as constructed in the Western imagination. more »
          • HTML5 & CSS: Structuring Pages
            March 30 1:00pm
            This session is being delivered online and simultaneously in room 144 in Wells Library in Bloomington. This is the online session, so please register for this session only if you plan to attend remotely. This workshop lasts 3.5 hours, more »
          • Developing Complex, Multi-Investigator, Multi-Institutional Proposals
            March 30 4:00pm
            The current funding environment favors large, complex, multi-institutional, multi-investigator projects. However, organizing a successful submission takes a great deal of planning and teamwork. This session will focus on exploring the distinctions between “standard” and “complex” submissions, navigating through issues of more »
          Thursday, March 30, 2017