• CLOSED
    August 24 12:00am
    closed more »
  • FINA Jr. World Championships
    August 24 12:00am
    swim meet more »
  • Start of School - Parking Information Table
    August 24 8:00am
    Information and resources on parking and all their services for new and returning students. more »
  • Top Hat Lunch and Learn
    August 24 11:30am
    Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
  • Top Hat Lunch and Learn
    August 24 11:30am
    Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
Thursday, August 24, 2017
    IU Calendar




    • CLOSED
      August 24 12:00am
      closed more »
    • FINA Jr. World Championships
      August 24 12:00am
      swim meet more »
    • Start of School - Parking Information Table
      August 24 8:00am
      Information and resources on parking and all their services for new and returning students. more »
    • Top Hat Lunch and Learn
      August 24 11:30am
      Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
    • Top Hat Lunch and Learn
      August 24 11:30am
      Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
    Thursday, August 24, 2017
      IU Calendar




      • CLOSED
        August 24 12:00am
        closed more »
      • FINA Jr. World Championships
        August 24 12:00am
        swim meet more »
      • Start of School - Parking Information Table
        August 24 8:00am
        Information and resources on parking and all their services for new and returning students. more »
      • Top Hat Lunch and Learn
        August 24 11:30am
        Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
      • Top Hat Lunch and Learn
        August 24 11:30am
        Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
      Thursday, August 24, 2017
        IU Calendar




        • CLOSED
          August 24 12:00am
          closed more »
        • FINA Jr. World Championships
          August 24 12:00am
          swim meet more »
        • Start of School - Parking Information Table
          August 24 8:00am
          Information and resources on parking and all their services for new and returning students. more »
        • Top Hat Lunch and Learn
          August 24 11:30am
          Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
        • Top Hat Lunch and Learn
          August 24 11:30am
          Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
        Thursday, August 24, 2017

          About This Event

          Summary

          Yogesh Pandit, Master’s in Bioinformatics Thesis Defense

          Title: Context Specific Text Mining For Annotating Protein Interactions With Experimental Evidence

          Thesis committee:

          • Mathew Palakal, Ph.D., Chair

          • Yunlong Liu, Ph.D.

          • Xiaowen Liu, Ph.D.

          Abstract:

          Proteins are the building blocks in a biological system. They interact with other proteins to make unique biological phenomenon. Protein-protein interactions play a valuable role in understanding the molecular mechanisms occurring in any biological system. Protein interaction databases are a rich source on protein interaction related information. They gather large amounts of information from published literature to enrich their data. Expert curators put in most of these efforts manually. The amount of accessible and publicly available literature is growing very rapidly. Manual annotation is a time consuming process. And with the rate at which available information is growing, it cannot be dealt with only manual curation. There need to be tools to process this huge amounts of data to bring out valuable gist than can help curators proceed faster. In case of extracting protein-protein interaction evidences from literature, just a mere mention of a certain protein by look-up approaches cannot help validate the interaction. Supporting protein interaction information with experimental evidence can help this cause. Also to avoid redundancy in curation efforts and for ease of accessibility, efforts are being put to relate manually curated information to standardized ontologies. In this study, we are applying machine learning based classification techniques to classify any given protein interaction related document into an interaction detection method. We use biological attributes and experimental factors, different combination of which define any particular interaction detection method. Then using predicted detection methods, proteins identified using named entity recognition techniques and decomposing the parts-of-speech composition we search for sentences with experimental evidence for a protein-protein interaction. We report an accuracy of 75.1% with a F-score of 47.6% on a dataset containing 2035 training documents and 300 test documents.

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          Contact Information

          Mary O'Neill
          moneill@iupui.edu

          Event Site --- None ---
          Registration --- None ---

          Event Schedule

          There are no upcoming dates for this event.

          IU Calendar




          • CLOSED
            August 24 12:00am
            closed more »
          • FINA Jr. World Championships
            August 24 12:00am
            swim meet more »
          • Start of School - Parking Information Table
            August 24 8:00am
            Information and resources on parking and all their services for new and returning students. more »
          • Top Hat Lunch and Learn
            August 24 11:30am
            Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
          • Top Hat Lunch and Learn
            August 24 11:30am
            Top Hat is an interactive teaching platform designed to make classroom lectures (as well as online assignments) more engaging and effective. Using Top Hat, you can conduct polls, ask auto-graded and open-ended questions, and even initiate discussions. Results are tabulated instantly as students respond on their mobile devices.Top Hat will be hos more »
          Thursday, August 24, 2017